Myosteatosis and prognosis in cancer: systematic review and meta-analysis

GFP Aleixo, SS Shachar, KA Nyrop, HB Muss… - Critical reviews in …, 2020 - Elsevier
Background The evidence that body composition parameters influence multiple cancer
outcomes is rapidly expanding. Excess adiposity deposits in muscle tissue, termed …

Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: a new paradigm beyond sarcopenia

H Ahn, DW Kim, Y Ko, J Ha, YB Shin, J Lee… - Ageing Research …, 2021 - Elsevier
Myosteatosis, which is excessive fat infiltration in the skeletal muscle, is now considered a
distinct disease from sarcopenia. Advances in imaging technique have made muscle …

Association of muscle and adiposity measured by computed tomography with survival in patients with nonmetastatic breast cancer

BJ Caan, EMC Feliciano, CM Prado, S Alexeeff… - JAMA …, 2018 - jamanetwork.com
Importance Sarcopenia (low muscle mass), poor muscle quality (low muscle radiodensity),
and excess adiposity derived from computed tomography (CT) has been related to higher …

[HTML][HTML] Sarcopenic obesity: hidden muscle wasting and its impact for survival and complications of cancer therapy

VE Baracos, L Arribas - Annals of Oncology, 2018 - Elsevier
Body composition, defined as the proportions and distribution of lean and fat tissues in the
human body, is an emergent theme in clinical oncology. Severe muscle depletion …

Approaches to assessment of muscle mass and myosteatosis on computed tomography: a systematic review

B Amini, SP Boyle, RD Boutin… - The Journals of …, 2019 - academic.oup.com
Abstract Background/Objective: There is increasing use of computed tomography (CT) in
sarcopenia research using a wide variety of techniques. We performed a systematic review …

Implications of low muscle mass across the continuum of care: a narrative review

CM Prado, SA Purcell, C Alish, SL Pereira… - Annals of …, 2018 - Taylor & Francis
Abnormalities in body composition can occur at any body weight. Low muscle mass is a
predictor of poor morbidity and mortality and occurs in several populations. This narrative …

Effects of weight loss and sarcopenia on response to chemotherapy, quality of life, and survival

AM Ryan, CM Prado, ES Sullivan, DG Power, LE Daly - Nutrition, 2019 - Elsevier
It has frequently been shown that patients with cancer are one of the largest hospital patient
groups with a prevalence for malnutrition. Weight loss is a frequent manifestation of …

Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis

W Yan, M Cao, X Ruan, L Jiang, S Lee, A Lemanek… - Nature cell …, 2022 - nature.com
A decline in skeletal muscle mass and low muscular strength are prognostic factors in
advanced human cancers. Here we found that breast cancer suppressed O-linked N …

Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta‐analysis

DSM Chan, R Vieira, L Abar, D Aune… - … Journal of Cancer, 2023 - Wiley Online Library
Previous evidence on postdiagnosis body fatness and mortality after breast cancer was
graded as limited‐suggestive. To evaluate the evidence on body mass index (BMI), waist …

[HTML][HTML] Sarcopenia associated with chemotherapy and targeted agents for cancer therapy

MP Davis, R Panikkar - Annals of palliative medicine, 2019 - apm.amegroups.org
Clinicians often believe that cachexia is caused by cancer and anorexia as a toxicity of
chemotherapy or targeted anti-cancer agents. It is now recognized that chemotherapy and …