Microbial transformation of dietary xenobiotics shapes gut microbiome composition

EJ Culp, NT Nelson, AA Verdegaal, AL Goodman - Cell, 2024 - cell.com
Diet is a major determinant of gut microbiome composition, and variation in diet-microbiome
interactions may contribute to variation in their health consequences. To mechanistically …

Navigating the B vitamins: Dietary diversity, microbial synthesis, and human health

Y Yang, Y Ke, X Liu, Z Zhang, R Zhang, F Tian, L Zhi… - Cell Host & Microbe, 2024 - cell.com
B vitamins are intricately involved in various physiological processes vital for health. Their
significance is complicated by the heterogeneous landscape of B vitamin distribution in diets …

[HTML][HTML] Dietary selective effects manifest in the human gut microbiota from species composition to strain genetic makeup

KD Huang, M Müller, P Sivapornnukul, AA Bielecka… - Cell reports, 2024 - cell.com
Diet significantly influences the human gut microbiota, a key player in health. We analyzed
shotgun metagenomic sequencing data from healthy individuals with long-term dietary …

Predicting the first steps of evolution in randomly assembled communities

J McEnany, BH Good - Nature Communications, 2024 - nature.com
Microbial communities can self-assemble into highly diverse states with predictable
statistical properties. However, these initial states can be disrupted by rapid evolution of the …

The underlying changes in serum metabolic profiles and efficacy prediction in patients with extensive ulcerative colitis undergoing fecal microbiota transplantation

X Wu, P Li, W Wang, J Xu, R Ai, Q Wen, B Cui, F Zhang - Nutrients, 2023 - mdpi.com
(1) Background: Fecal microbiota transplantation (FMT) is an effective treatment for
ulcerative colitis (UC). Metabolomic techniques would assist physicians in clinical decision …

Quantifying the adaptive landscape of commensal gut bacteria using high-resolution lineage tracking

DPGH Wong, BH Good - Nature Communications, 2024 - nature.com
Gut microbiota can adapt to their host environment by rapidly acquiring new mutations.
However, the dynamics of this process are difficult to characterize in dominant gut species in …

Neutralizing gut-derived lipopolysaccharide as a novel therapeutic strategy for severe leptospirosis

X Xie, X Chen, S Zhang, J Liu, W Zhang, Y Cao - Elife, 2024 - elifesciences.org
Leptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp.
Humans and some mammals can develop severe forms of leptospirosis accompanied by a …

Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance

R Unni, NA Andreani, M Vallier, SS Heinzmann… - Gut …, 2023 - Taylor & Francis
Inflammatory bowel disease (IBD) is a persistent inflammatory condition that affects the
gastrointestinal tract and presents significant challenges in its management and treatment …

Evolutionary Medicine for Chronic Inflammatory Diseases of the Gut: More Than a Clinical Fantasy?

NA Andreani, D Unterweger, S Schreiber, JF Baines - Gastroenterology, 2024 - Elsevier
Evolutionary medicine applies the principles of evolution to improve patient health1, 2. While
47 several clinical disciplines3–5 already incorporate evolution, it also begins to receive …

Infection marks gut commensals

A Taglialegna - Nature Reviews Microbiology, 2023 - nature.com
Infection marks gut commensals | Nature Reviews Microbiology Skip to main content Thank
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