Background Melanoma aetiology has been proposed to have two pathways, which are
determined by naevi and type of sun exposure and related to the anatomical site where …

Background A high total body naevus count is the highest risk factor for melanoma; the
phenotype of red hair colour, freckling and pale skin that burns easily, produced by MC1R R …

Summary Background Hypomorphic MC1R variants are the most prevalent genetic
determinants of melanoma risk in the white population. However, the genetic background of …

IRF4, MTAP, PLA2G6, and MITF have been shown to strongly influence TNC, and many
other nevus-associated genes have been recognized (Duffy et al., 2018). Dermoscopy has …

Benign naevi are closely linked to melanoma, as risk factors, simulators, or sites of
melanoma formation. There is a heavy genetic overlap between the two lesions, a shared …

Background Iris naevi and iris freckles have a frequency of 4% and 50% in the European
population, respectively. They are associated with dysplastic naevi, but few studies have …

Genetic susceptibility to nevi may affect the risk of developing melanoma, since common
and atypical nevi are the main host risk factors implicated in the development of cutaneous …

Background Naevi number changes with age. Thus, a better understanding of naevus
biology will shed more light on the genetic and environmental factors involved in melanoma …

Background Childhood and adolescence are the most active periods for nevi development,
which provide insights into nevogenesis. Objectives To evaluate the clinical and …

Examining Evidence for a Causal Association between Telomere Length and Nevus Count
Examining Evidence for a Causal Association between Telomere Length and Nevus Count J …