Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

STUDY QUESTION How does in vitro culture alter the human ovarian cortical extracellular
matrix (ECM) network structure? SUMMARY ANSWER The ECM composition and …

Context Osteoporosis results from disturbances in bone formation and resorption. Recent
nonhuman data suggest that the reproductive hormone kisspeptin directly stimulates …

Kisspeptin and its receptor are central to reproductive health acting as key regulators of the
reproductive endocrine axis in humans. Kisspeptin is most widely recognised as a regulator …

Kisspeptin is a hypothalamic neuropeptide that acts via the hypothalamus to stimulate
hypothalamic gonadotrophin-releasing hormone secretion and downstream gonadotrophin …

There is considerable evidence that synchronized activity within a reciprocally connected
population of cells in the arcuate nucleus (ARC) coexpressing kisspeptin, neurokinin B …

Kisspeptins are the family of neuropeptide products of the KISS-1 gene that exert the
biological action by binding with the G-protein coupled receptor 54 (GPR54), also known as …