Epidermal growth factor receptor targeting in colorectal carcinoma: antibodies and patient-derived organoids as a smart model to study therapy resistance
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide.
Therefore, the need for new therapeutic strategies is still a challenge. Surgery and …
Therefore, the need for new therapeutic strategies is still a challenge. Surgery and …
Reply to Dr. Rafael Rosell: Shedding some light on the unresolved issue of YAP1 Ser397 phosphorylation in cancer
A Río-Vilariño, J García-Foncillas, A Cebrián - British Journal of Cancer, 2024 - nature.com
We want to thank Dr. Rafael Rosell for his comments about our study. We agree with his
comment on the well-known roles of YAP1's Ser397 phosphorylation [1]. It is known that …
comment on the well-known roles of YAP1's Ser397 phosphorylation [1]. It is known that …
Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism
M Li, H Jin, Y Liu, Z Wang, L Li, T Wang, X Wang… - bioRxiv, 2024 - biorxiv.org
Innate immune cells can acquire a memory phenotype, termed trained immunity, but the
mechanism underlying the regulation of trained immunity remains largely elusive. Here, we …
mechanism underlying the regulation of trained immunity remains largely elusive. Here, we …
RE: Reply to Rio-Vilariño and colleagues' article and misconception about YAP1 Ser 397 phosphorylation function
R Rosell - British Journal of Cancer, 2024 - nature.com
I read the article titled “Inhibition of the AURKA/YAP1 axis is a promising therapeutic option
for overcoming cetuximab resistance in colorectal cancer stem cells,” published by Rio …
for overcoming cetuximab resistance in colorectal cancer stem cells,” published by Rio …