An overview on the therapeutics of neglected infectious diseases—Leishmaniasis and Chagas diseases
K Chanda - Frontiers in Chemistry, 2021 - frontiersin.org
Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious
diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas …
diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas …
A review on development of bio-active thiosemicarbazide derivatives: Recent advances
There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …
with diverse biological activities in recent years. Therefore, many scientists have prepared …
[HTML][HTML] Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases
A Henriquez-Figuereo, C Morán-Serradilla… - European Journal of …, 2023 - Elsevier
Neglected tropical diseases (NTDs) encompass a group of infectious diseases with a
protozoan etiology, high incidence, and prevalence in developing countries. As a result …
protozoan etiology, high incidence, and prevalence in developing countries. As a result …
Cheminformatics-based discovery of new organoselenium compounds with potential for the treatment of cutaneous and visceral leishmaniasis
Leishmaniasis affects more than 12 million humans globally and a further 1 billion people
are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis coupled …
are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis coupled …
Tetrahydrobenzo [h] quinoline derivatives as a novel chemotype for dual antileishmanial-antimalarial activity graced with antitubercular activity: Design, synthesis and …
TM Ibrahim, G Abada, M Dammann, RM Maklad… - European Journal of …, 2023 - Elsevier
Derivatives with tetrahydrobenzo [h] quinoline chemotype were synthesized via one-pot
reactions and evaluated for their antileishmanial, antimalarial and antitubercular activities …
reactions and evaluated for their antileishmanial, antimalarial and antitubercular activities …
Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and in silico studies
New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-
pot fashion. The in vitro antileishmanial activity against Leishmania major promastigote and …
pot fashion. The in vitro antileishmanial activity against Leishmania major promastigote and …
Synthesis, antimalarial, antileishmanial evaluation, and molecular docking study of some 3-aryl-2-styryl substituted-4(3H)-quinazolinone derivatives
Quinazolinones are a diverse group of nitrogen-containing heterocyclic compounds with
promising antimalarial and antileishmanial activities. Herein, some 3-aryl-2-styryl substituted …
promising antimalarial and antileishmanial activities. Herein, some 3-aryl-2-styryl substituted …
Computational evaluation of the inhibitory potential of some urea, thiourea, and selenourea derivatives of diselenides against leishmaniasis: 2D-QSAR …
Leishmaniasis affects more than twelve million people globally and a further one billion
people are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis …
people are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis …
Virtual screening and the in vitro assessment of the antileishmanial activity of lignans
M dos Santos Maia, JP Raimundo e Silva… - Molecules, 2020 - mdpi.com
Leishmaniasis is endemic in at least 98 countries. Due to the high toxicity and resistance
associated with the drugs, we chose lignans as an alternative, due to their favorable …
associated with the drugs, we chose lignans as an alternative, due to their favorable …
[HTML][HTML] Hidden potential of hydrazinecarboxamides (semicarbazides) as potential antimicrobial agents: A review
M Krátký, NH Houngbedji, J Vinšová - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Hydrazinecarboxamides (semicarbazides) are increasingly recognized as a versatile
scaffold in developing potential antimicrobial agents. In addition to a brief overview of the …
scaffold in developing potential antimicrobial agents. In addition to a brief overview of the …