A review of the background, operating parameters and applications of microemulsion liquid chromatography (MELC)

A Marsh, BJ Clark, KD Altria - Journal of separation science, 2005 - Wiley Online Library
Microemulsions are dispersions of nanometre‐sized droplets of an immiscible liquid within
another liquid. Droplet formation is facilitated by the addition of surfactants and often also …

Simultaneous determination of some cholesterol-lowering drugs in their binary mixture by novel spectrophotometric methods

HM Lotfy, MAM Hegazy - Spectrochimica Acta Part A: Molecular and …, 2013 - Elsevier
Four simple, specific, accurate and precise spectrophotometric methods manipulating ratio
spectra were developed and validated for simultaneous determination of simvastatin (SM) …

Significance of stressor media on the stability of statins: a critical assessment

DS Lalchandani, L Chenkual, M Mariappayan… - Chemical Papers, 2022 - Springer
Statins are the most prescribed HMG CoA reductase inhibitors for the treatment of anti-
hyperlipidemia either alone or in combination with other pharmacotherapeutic agents …

[PDF][PDF] Absorbance subtraction and amplitude modulation as novel spectrophotometric methods for the analysis of binary mixtures

HM Lotfy - Int. J. Pharm. Pharm. Sci, 2014 - researchgate.net
Objective: To develop two novel, simple, specific and accurate spectrophotometric methods
for simultaneous determination of binary mixtures, without prior separation steps. Methods …

[PDF][PDF] Determination of simvastatin and ezatimibe in combined tablet dosage forms by constant center spectrophotometric method

HM Lotfy - Int J Pharm Pharm Sci, 2012 - researchgate.net
ABSTRACT A novel, simple, specific and accurate spectrophotometric method is developed
and validated for determination of simvastatin (SM) and ezatimibe (EZ) namely; constant …

Simultaneous determination of loratadine and desloratadine in pharmaceutical preparations using liquid chromatography with a microemulsion as eluent

DT El-Sherbiny, N El-Enany, FF Belal… - Journal of pharmaceutical …, 2007 - Elsevier
A rapid HPLC procedure for analytical quality control of pharmaceutical preparations
containing the antihistaminic drug substance loratadine and/or its analog desloratadine …

Desirability-based optimization and its sensitivity analysis for the perindopril and its impurities analysis in a microemulsion LC system

A Malenović, Y Dotsikas, M Mašković… - Microchemical …, 2011 - Elsevier
In the current paper the application of multiobjective optimization (MOOP) technique, via
Derringer's desirability function, to a microemulsion liquid chromatographic (MELC) method …

Microemulsion high performance liquid chromatography (MELC) method for the determination of terbutaline in pharmaceutical preparation

MS Althanyan, KH Assi, BJ Clark, J Hanaee - Journal of pharmaceutical and …, 2011 - Elsevier
A robust and sensitive microemulsion HPLC (MELC) method using oil-in-water
microemulsion mobile phase was developed and used for the determination of terbutaline in …

Development of liquid chromatographic method for fosinoprilat determination in human plasma using microemulsion as eluent

B Jancic, D Ivanovic, M Medenica, A Malenovic… - … of Chromatography a, 2005 - Elsevier
Fosinopril sodium presents a prodrug for the active angiotensin converting enzyme (ACE)
inhibitor, fosinoprilat. The dual elimination of fosinoprilat by the liver and the kidney …

Oil-in-water microemulsion liquid chromatography

E Peris-García, N Pankajkumar-Patel… - Separation & …, 2020 - Taylor & Francis
Oil-in-water microemulsions (O/W MEs) are obtained spontaneously by mixing two
immiscible liquids (water and oil) in the presence of a surfactant. A co-surfactant is also often …