The Mannich reaction is one of the most important types of organic chemistry fundamental
reactions. It is a crucial stage in the production of various medicines, natural goods, and …

Inflammation is the natural defense mechanism against any external stimuli in the human
body and it saves us from foreign entities that may alter our bodies' normal functioning. Any …

Introduction One of the most common problems of diabetes are diabetic foot ulcers (DFUs).
According to National Institute for Health, initial management of DFUs can decrease the …

Javanese turmeric rhizome (Curcuma xanthorrhiza Roxb.) has been known to have many
health benefits as antibacterial, anti-inflammatory, antidiabetic and anticancer. The purpose …

A series of N-Mannich base derivatives of 2-phenyl-2-imidazoline with substituted amines (1–
13) were designed, synthesized, and characterized by spectroanalytical techniques. The …

Multidrug resistance and infectious disease have enormous spread despite drug discovery
and development advancements. 1, 2, 4-triazoles have been extensively studied, playing an …

Acetylcholinesterase (AChE) enzyme and myeloid differentiation 2 protein (MD2) are two
critical proteins involved in Alzheimer's disease (AD). Since the nature of the active site of …

Mannich bases are beta-amino ketone-carrying compounds that are the end products of the
Mannich reaction. The Mannich reaction is essential in the synthesis of nitrogen-containing …

Cases of diabetes are significantly increasing year by year, attracting the attention of
medical professionals and researchers to focus on diabetes and its underlying …

ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF SYNTHESIZED MANNICH BASE
DERIVATIVES OF (2E,6E)-2-[(4-HYDROXY-3-METHOXYPHENYL)METH Page 1 ISSN …