How Molecular Packing Affects the Thermodynamic Parameters of Cocrystal Formation: The Case of Carbamazepine Cocrystals

AN Manin, DE Boycov, OR Simonova… - Crystal Growth & …, 2023 - ACS Publications
In the present work, the thermodynamic aspects related to the driving force of cocrystal
formation and their stability were studied for a series of 1: 1 carbamazepine (CBZ) …

Multicomponent Crystals of Amitriptyline as Potential Controlled-Release Systems: Synthesis, Crystal Packing Analysis, and Dissolution Study

AP Voronin, AG Ramazanova, AO Surov… - Crystal Growth & …, 2023 - ACS Publications
In the present work, for the first time, a crystal engineering approach was systematically
applied to produce novel crystalline forms of the tricyclic antidepressant amitriptyline (AMT) …

Cocrystals of polynitrogen compounds as a basis for promising energetic materials: crystal structure prediction methods, their experimental verification, and evaluation …

NM Baraboshkin, VP Zelenov, DV Khakimov… - Russian Chemical …, 2024 - Springer
The review concerns methods for modeling the crystal structure of polynitrogen compounds
and their cocrystals. The state of the art in chemical research into (co) crystals of energetic …

Characterization of Drug with Good Glass-Forming Ability Loaded Mesoporous Silica Nanoparticles and Its Impact Toward in vitro and in vivo Studies

A Budiman, G Anastasya, AL Handini… - International Journal …, 2024 - Taylor & Francis
Solid oral dosage forms are mostly preferred in pharmaceutical formulation development
due to patient convenience, ease of product handling, high throughput, low manufacturing …

Supramolecular Organization in Salts of Riluzole with Dihydroxybenzoic Acids—The Key Role of the Mutual Arrangement of OH Groups

AP Voronin, AO Surov, AV Churakov, MV Vener - Pharmaceutics, 2023 - mdpi.com
Intermolecular interactions, in particular hydrogen bonds, play a key role in crystal
engineering. The ability to form hydrogen bonds of various types and strengths causes …

Cocrystal and Coamorphous Solid Forms of Enzalutamide with Saccharin: Structural Characterization and Dissolution Studies

J Prashanth, KV Drozd, GL Perlovich… - Crystal Growth & …, 2022 - ACS Publications
Cocrystallization and coamorphization are similar yet independent approaches toward
modifying various pharmaceutically relevant properties of modern drug compounds, in …

Preparation and structure analysis of non-covalent interactions mediated 2D-3D supramolecular adducts from 6-methylnicotinamide and carboxylic acids

Y Wu, J Zhou, S Jin, B Liu, C Shi, D Wang - Journal of Molecular Structure, 2022 - Elsevier
methylnicotinamide was utilized to create co-crystal/salts for the first time. By introducing it
into the co-crystallization system based on different carboxylic acids of mono-to dicarboxylic …

Anisotropy, segmental dynamics and polymorphism of crystalline biogenic carboxylic acids

V Pokorný, P Touš, V Štejfa, K Růžička… - Physical Chemistry …, 2022 - pubs.rsc.org
Carboxylic acids of the Krebs cycle possess invaluable biochemical significance. Still, there
are severe gaps in the availability of thermodynamic and crystallographic data, as well as …

Preparation and structure analysis of non-covalent interactions directed 11 adducts from 2-amino-5-methylthiazole and organic acids

P Wang, X Wu, S Jin, Y Lu, B Liu, K Dong… - Journal of Molecular …, 2022 - Elsevier
Abstract The 2-amino-5-methylthiazole was used in the construction of adducts. By
introducing it into the co-crystallization system based on different organic acids of mono-to …

Thermochemistry of fusion of benzocaine and S-naproxen between 298.15 K and Tm studied by solution and fast scanning calorimetry

MI Yagofarov, AA Sokolov, MA Ziganshin… - Journal of Thermal …, 2023 - Springer
Thermodynamic parameters of fusion define the solubility and stability of the crystalline
materials and thus are important in the field of pharmaceutics. However, determining these …