High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - National Acad Sciences
Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - pure.mpg.de
Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - pubmed.ncbi.nlm.nih.gov
Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - ui.adsabs.harvard.edu
Stress exposure is associated with increased risk for a wide range of psychiatric disorders.
The individual long-term impact of stress may be moderated by genetic variants. Using a …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders.

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - europepmc.org
Results Identification of Allele-Specific Regulatory Elements Modulated by a Glucocorticoid
Receptor Agonist in Response to Stress Using STARR-seq. We conducted an enhancer …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders.

S Penner-Goeke, M Bothe, N Rek… - Proceedings of the …, 2023 - europepmc.org
Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …