… Using fine-mapping and functional genomic data, we prioritise 19 genes based on protein-…
, particularly synaptic organisation, differentiation and transmission. We identify biological …

… Here, in a two-stage genome-wide association study of up to … associations at 287 distinct
genomic loci. Associations were … Using fine-mapping and functional genomic data, we identify …

… Here, in a two-stage genome-wide association study of up to … associations at 287 distinct
genomic loci. Associations were … Using fine-mapping and functional genomic data, we identify …

… Estimated odds ratios for DNA variants at example synaptic gene loci associated with
schizophrenia and their observed frequency in schizophrenia cases in the corresponding studies. …

… Recent genomic findings identify many hundreds of genomic loci that are associated with …
how genomic findings might be used to provide specific insights into the biological basis of …

… adhesion, acting biology of their adhesive interactions, and now … of in which the CNS synapse
is subdivided into unrelated … The new discovery of a unique genomic locus encoding neu…

… Some lncRNAs regulate brain development and synaptic plasticity. In Alzheimer’s
disease (AD), several lncRNAs have been demonstrated to regulate β-amyloid production/generation, …

… was assembled from previous GWAS (genome-wide association studies) … Loci) was used
to identify biological relationships between the selected genes. We used the GRAIL biological …

… Here, in a two-stage genome-wide association study of up to … associations at 287 distinct
genomic loci. Associations were … Using fine-mapping and functional genomic data, we identify …

… We link upstream genomic rearrangement of the PTCHD1 locus with ASD and employ iPSCs
and genome editing to determine the functional consequences of PTCHD1 locus deletions …