Single-cell transcriptomic analysis of Alzheimer's disease

H Mathys, J Davila-Velderrain, Z Peng, F Gao… - Nature, 2019 - nature.com
… To classify the major cell types in the aged cortex, we pre-clustered all cells jointly across …
We identified and annotated the major cell types of the human brain by interrogating the …

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease

H Liu, T Doke, D Guo, X Sheng, Z Ma, J Park, HMT Vy… - Nature …, 2022 - nature.com
… Human kidney single-cell open chromatin information Next, we wanted to identify cell types
… kidney single-cell accessibility maps enable identification of cell types and genes related to …

[PDF][PDF] Single-cell transcriptome analysis in plants: advances and challenges

R Shaw, X Tian, J Xu - Molecular Plant, 2021 - cell.com
… Gazing into the crystal ball, we see an ever-increasing role for single-cell transcriptomics
analysis in plant research and breeding. However, the rapidly growing field of single-cell

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

M Uhlen, MJ Karlsson, W Zhong, A Tebani, C Pou… - Science, 2019 - science.org
Transcriptome analysis of isolated human immune cell populations We used flow cytometric
sorting to allow whole-genome transcriptome analysis of the major blood cell types from …

Single-cell transcriptomic analysis of tumor heterogeneity

HM Levitin, J Yuan, PA Sims - Trends in cancer, 2018 - cell.com
type mature and identify key markers of drug response, more targeted approaches to single-cell
… In sum, we believe that large-scale, single-cell transcriptomics will significantly impact …

Single-cell transcriptomic analysis of mouse neocortical development

L Loo, JM Simon, L Xing, ES McCoy… - Nature …, 2019 - nature.com
… in developing cortical cell types, we hierarchically clustered the cellular expression profiles of
cellular expression at the individual cell type level and summarized across broader cellular

[HTML][HTML] Cross-species analysis of single-cell transcriptomic data

MER Shafer - Frontiers in cell and developmental biology, 2019 - frontiersin.org
cell types across … -cell transcriptomics, and methods to classify cell type homologies and
diversifications. Many tools currently exist for analyzing single cell data and identifying cell types

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types

SJ Carmona, SA Teichmann, L Ferreira… - Genome …, 2017 - genome.cshlp.org
… As reliable antibodies to isolate pure immune cell populations in fish species are not available,
we used single-cell transcriptome analysis of zebrafish Tg(lck:GFP) cells. This transgenic …

A single–cell type transcriptomics map of human tissues

M Karlsson, C Zhang, L Méar, W Zhong, A Digre… - Science …, 2021 - science.org
… -cell transcriptomics analysis with spatial antibody-based protein profiling to create a high-resolution
single–cell type … -coding genes in 192 individual cell type clusters. An expression …

Single-cell transcriptome analysis of endometrial tissue

K Krjutškov, S Katayama, M Saare… - Human …, 2016 - academic.oup.com
… the full transcriptome of endometrial stromal and epithelial cells at the single-cell level? … We
describe here a single-cell separation, transcriptome sequencing and data analysis pipeline, …