Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

J Park, R Shrestha, C Qiu, A Kondo, S Huang, M Werth… - Science, 2018 - science.org
… cataloged mouse kidney cell types in an unbiased manner by using droplet-based single-cell
One of the most striking results of our analysis of the mouse kidney was the identification of …

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk

AN Combes, B Phipson, KT Lawlor, A Dorison… - …, 2019 - journals.biologists.com
… Here, we describe the generation and analysis of 6732 single cell transcriptomes from
the fetal mouse kidney [embryonic day (E)18.5] and 7853 sorted nephron progenitor cells (E14.5). …

Expression and function of P-glycoprotein in a mouse kidney cell line

S Ernest, E Bello-Reuss - … Journal of Physiology-Cell …, 1995 - journals.physiology.org
… was not detected in mouse kidney or TKPTS cells by Northern blot analysis. Consistent with
… mRNA in mouse kidney or TKPTS cells (data not shown). Because the whole mouse kidney

[HTML][HTML] High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population

JW Mugford, J Yu, A Kobayashi, AP McMahon - Developmental biology, 2009 - Elsevier
… In conclusion, transcriptional analysis has defined new cellular domains within the kidney
progenitor compartments. Furthermore, virtually all cells within the nephrogenic zone can be …

[PDF][PDF] Global quantification of tissue dynamics in the developing mouse kidney

KM Short, AN Combes, J Lefevre, AL Ju, KM Georgas… - Developmental cell, 2014 - cell.com
… defining kidney development. Here we report a comprehensive, quantitative, multiscale
analysis of mammalian kidney development in which we measure changes in cell number, …

[PDF][PDF] Single-cell profiling reveals sex, lineage, and regional diversity in the mouse kidney

A Ransick, NO Lindström, J Liu, Q Zhu, JJ Guo… - Developmental cell, 2019 - cell.com
… In conclusion, Kidney Cell Explorer will facilitate access to our data and analysis of these
data by the academic and clinical research communities. Further, the overall strategy adopted …

Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

Y Kirita, H Wu, K Uchimura… - Proceedings of the …, 2020 - National Acad Sciences
… (D) Deconvolution analysis of bulk RNA-seq mouse kidney IRI dataset using gene sets
specific for healthy PT, injured PT, and failed repair PT. *P < 0.05; **P < 0.01; ***P < 0.001, one-…

Oxidative stress decreases klotho expression in a mouse kidney cell line

M Mitobe, T Yoshida, H Sugiura, S Shirota… - Nephron Experimental …, 2005 - karger.com
… that is predominantly expressed in the kidney and brain. The … Analysis of the pathophysiology
of kl –/– mice is expected to … mRNA is predominantly observed in the kidney [1]. Several …

A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model

B Dai, V David, A Martin, J Huang, H Li, Y Jiao, W Gu… - 2012 - journals.plos.org
… To identify FGF23 responsive genes in the kidney that … analysis of gene expression profiles
in the kidney of the Collagen 4 alpha 3 null mice (Col4a3 −/− ) model of progressive kidney

A new method for large scale isolation of kidney glomeruli from mice

M Takemoto, N Asker, H Gerhardt, A Lundkvist… - The American journal of …, 2002 - Elsevier
… The method thus allows for transcript profiling and proteomic analysis of … mouse kidney, 11
we conclude that our method allows for isolation of most glomeruli present in a mouse kidney, …