DL Gisch, M Brennan, BB Lake, J Basta… - Nature …, 2024 - nature.com
… Cell-type specific open chromatin in the reference cell state … data to better understand the celltype-specific open chromatin signature across the kidney’s diverse range of celltypes. The …
C Guo, SA Morris - Current opinion in genetics & development, 2017 - Elsevier
… chromatinlandscape, considering how the mechanistic relationship between nuclear organization and cell identity will be crucial to unlocking the full potential of cell fate engineering. …
… cell nucleus. Moreover, the structure and location of genetic loci display celltype-specific … the interdependence of chromatin structure and nuclear function in mammalian cells. In this …
SW Criscione, YV Teo, N Neretti - Trends in Genetics, 2016 - cell.com
… Senescent cells undergo dramatic alterations to their chromatinlandscape that affect genome … of the role of chromatin and chromosome organization in cellular senescence. …
… New candidate cell-type-specific enhancers were identified for multiple ENCODE celltypes in … We conclude that large SOMs trained on chromatin data from multiple celltypes provide a …
N Kourtis, Q Wang, B Wang, E Oswald, C Adler… - Nature cancer, 2022 - nature.com
… -cell assay technology for transposase-accessible chromatin … Through surveying the chromatinlandscapes of T cells of … , we observe cell-type-specific and tissue-specific chromatin …
… cells in two biological contexts. First, we mapped the single-cellchromatin accessibility landscape of … humans, which revealed chromatin states of progenitor cells and the regulatory …
H Luo, Y Xi, W Li, J Li, Y Li, S Dong… - Human molecular …, 2017 - academic.oup.com
… polycomb-repressed chromatin played a role in repressing the irrelevant celltype-specific … ) marked the genes crucial for cell identity maintenance. Chromatin structure at NSRs and …
MI Love, MR Huska, M Jurk, R Schöpflin… - Nucleic acids …, 2017 - academic.oup.com
… celltypes than for celltype-specific target genes. Given that GR almost exclusively binds accessible chromatin, we propose that celltype-… chromatin accessibility is typically celltype-…