Accurate biomarkers for predicting COVID‐19 severity have remained an unmet need due to
an incomplete understanding of virus pathogenesis and heterogeneity among patients …

SARS‐CoV‐2 is a novel betacoronavirus which infects the lower respiratory tract and can
cause coronavirus disease 2019 (COVID‐19), a complex respiratory distress syndrome …

The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …

Reports of post-acute COVID-19 syndrome, in which the inflammatory response persists
even after SARS-CoV-2 has disappeared, are increasing, but the underlying mechanisms of …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of
the respiratory system can progress to a multisystemic disease with aberrant inflammatory …

Worldwide COVID-19 infection poses an enormous risk to public health and an alarming
global socioeconomic burden. The impact of the COVID-19 pandemic on individuals with …

Rationale SARS-CoV-2 infection of the respiratory system can progress to a life threatening
multi-systemic disease, mediated via an excess of cytokines (“cytokine storm”), but the …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …

Abstract Coronavirus disease 2019 (COVID‐19) is especially severe in aged patients,
defined as 65 years or older, for reasons that are currently unknown. To investigate the …