The cross-pathway control gene of Neurospora crassa, cpc-1, encodes a protein similar to GCN4 of yeast and the DNA-binding domain of the oncogene v-jun …

JL Paluh, MJ Orbach, TL Legerton… - Proceedings of the …, 1988 - National Acad Sciences
Expression of the gene cpc-1 is required for cross-pathway-mediated regulation of amino
acid-biosynthetic genes in Neurospora crassa. We have cloned cpc-1 and present an …

cpc-1, the General Regulatory Gene for Genes of Amino Acid Biosynthesis in Neurospora crassa, Is Differentially Expressed during the Asexual Life Cycle

DJ Ebbole, JL Paluh, M Plamann… - … and cellular biology, 1991 - Taylor & Francis
CPC1, the principal regulatory protein required for cross-pathway control of amino acid
biosynthetic genes in Neurospora crassa, contains a domain similar to the DNA-binding …

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

PK Vogt, TJ Bos, RF Doolittle - Proceedings of the National …, 1987 - National Acad Sciences
The product of the recently described oncogene jun shows significant amino acid sequence
homology with the GCN4 yeast transcriptional activator protein. The similarity is restricted to …

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

K Struhl - Cell, 1987 - cell.com
The jun oncoprotein, which causes sarcomas in chickens, and the DNA-binding domain of
yeast GCN4, which coordinately regulates the expression of amino acid biosynthetic genes …

Transcriptional Autoregulation and Inhibition of mRNA Translation of Amino Acid Regulator Gene cpcA of Filamentous FungusAspergillus nidulans

B Hoffmann, O Valerius, M Andermann… - Molecular biology of …, 2001 - Am Soc Cell Biol
The CPCA protein of the filamentous fungus Aspergillus nidulans is a member of the c-Jun-
like transcriptional activator family. It acts as central transcription factor of the cross-pathway …

Human Proto-Oncogene c-jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

D Bohmann, TJ Bos, A Admon, T Nishimura, PK Vogt… - Science, 1987 - science.org
Nuclear oncogene products have the potential to induce alterations in gene regulation
leading to the genesis of cancer. The biochemical mechanisms by which nuclear …

[HTML][HTML] cpc-3, the Neurospora crassa homologue of yeast GCN2, encodes a polypeptide with juxtaposed eIF2α kinase and histidyl-tRNA synthetase-related domains …

E Sattlegger, AG Hinnebusch, IB Barthelmess - Journal of Biological …, 1998 - ASBMB
Based on characteristic amino acid sequences of kinases that phosphorylate the α subunit
of eukaryotic translation initiation factor 2 (eIF2α kinases), degenerate oligonucleotide …

Insertional mutagenesis in Neurospora crassa: cloning and molecular analysis of the preg+ gene controlling the activity of the transcriptional activator NUC-1.

S Kang, RL Metzenberg - Genetics, 1993 - academic.oup.com
The transcriptional activator NUC-1 controls the transcription of the genes for phosphorus
acquisition enzymes, and its activity is regulated by the negative regulatory factors, PREG …

A gene activated by growth factors is related to the oncogene v-jun.

K Ryder, LF Lau, D Nathans - Proceedings of the National …, 1988 - National Acad Sciences
We have recently identified by cDNA cloning a set of genes that are rapidly activated in
cultured mouse cells by protein growth factors. Here we report that the nucleotide sequence …

Biochemical analysis of transcriptional activation by Jun: differential activity of c-and v-Jun

D Bohmann, R Tjian - Cell, 1989 - cell.com
The human proto-oncogene product, cJun, is a member of the AP-1 family of transcription
factors, which mediate the regulation of gene expression in response to extracellular …