Cardiopulmonary changes with aeration of the newborn lung

SB Hooper, GR Polglase, CC Roehr - Paediatric respiratory reviews, 2015 - Elsevier
The newborn's transition from fetal to neonatal life includes aeration of the lungs,
establishment of pulmonary gas exchange and changing the fetal circulation into the adult …

Role of aeration in the physiological adaptation of the lung to air-breathing at birth

SB Hooper, R Harding - Current Respiratory Medicine Reviews, 2005 - ingentaconnect.com
At birth, the successful transition to extra-uterine life is dependent upon the ability of the lung
to take over the role of respiratory gas-exchange. Before birth, the future airways of the lungs …

Issues in cardiopulmonary transition at birth

SB Hooper, C Roberts, J Dekker, AB Te Pas - Seminars in Fetal and …, 2019 - Elsevier
The transition from fetal to newborn life involves a complex series of physiological events
that commences with lung aeration, which is thought to involve 3 mechanisms. Two …

Establishing functional residual capacity at birth

SB Hooper, AB Te Pas, RA Lewis, CJ Morley - NeoReviews, 2010 - publications.aap.org
Major changes in cardiovascular and respiratory physiology underpin the successful
transition from fetal to neonatal life, and it is now apparent that lung aeration and the onset of …

Inspiration regulates the rate and temporal pattern of lung liquid clearance and lung aeration at birth

ML Siew, MJ Wallace, MJ Kitchen… - Journal of applied …, 2009 - journals.physiology.org
At birth, the initiation of pulmonary gas exchange is dependent on air entry into the lungs,
and recent evidence indicates that pressures generated by inspiration may be involved. We …

Cardiovascular transition at birth: a physiological sequence

SB Hooper, AB Te Pas, J Lang, JJ van Vonderen… - Pediatric …, 2015 - nature.com
The transition to newborn life at birth involves major cardiovascular changes that are
triggered by lung aeration. These include a large increase in pulmonary blood flow (PBF) …

Ventilation/perfusion mismatch during lung aeration at birth

JAR Lang, JT Pearson, AB Te Pas… - Journal of Applied …, 2014 - journals.physiology.org
At birth, the transition to newborn life is triggered by lung aeration, which stimulates a large
increase in pulmonary blood flow (PBF). Current theories predict that the increase in PBF is …

Increase in pulmonary blood flow at birth: role of oxygen and lung aeration

JAR Lang, JT Pearson, C Binder‐Heschl… - The Journal of …, 2016 - Wiley Online Library
Key points There is no well‐established, direct correlation between local aeration and
perfusion in the lungs immediately following birth. In a new study of simultaneous X‐ray …

The pulmonary circulation in neonatal respiratory failure

S Lakshminrusimha - Clinics in perinatology, 2012 - Elsevier
The pulmonary circulation rapidly adapts at birth to establish lungs as the site of gas
exchange. Abnormal transition at birth and/or parenchymal lung disease can result in …

Gradual aeration at birth is more lung protective than a sustained inflation in preterm lambs

DG Tingay, PM Pereira-Fantini, R Oakley… - American journal of …, 2019 - atsjournals.org
Rationale: The preterm lung is susceptible to injury during transition to air breathing at birth.
It remains unclear whether rapid or gradual lung aeration at birth causes less lung injury …