The use of TKM-100802 and convalescent plasma in 2 patients with Ebola virus disease in the United States

CS Kraft, AL Hewlett, S Koepsell… - Clinical Infectious …, 2015 - academic.oup.com
Abstract Background. The current West Africa Ebola virus disease (EVD) outbreak has
resulted in multiple individuals being medically evacuated to other countries for clinical …

Experimental treatment of Ebola virus disease with TKM-130803: a single-arm phase 2 clinical trial

J Dunning, F Sahr, A Rojek, F Gannon, G Carson… - PLoS …, 2016 - journals.plos.org
Background TKM-130803, a small interfering RNA lipid nanoparticle product, has been
developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in …

Evaluation of convalescent plasma for Ebola virus disease in Guinea

J Van Griensven, T Edwards… - … England Journal of …, 2016 - Mass Medical Soc
Background In the wake of the recent outbreak of Ebola virus disease (EVD) in several
African countries, the World Health Organization prioritized the evaluation of treatment with …

Administration of brincidofovir and convalescent plasma in a patient with Ebola virus disease

DF Florescu, AC Kalil, AL Hewlett… - Clinical Infectious …, 2015 - academic.oup.com
Abstract From 2014 to May 2015,> 26 000 Ebola virus disease (EVD) cases were reported
from West Africa. We present a patient with EVD who received brincidofovir and …

Clinical management of Ebola virus disease in the United States and Europe

TM Uyeki, AK Mehta, RT Davey Jr… - … England Journal of …, 2016 - Mass Medical Soc
Background Available data on the characteristics of patients with Ebola virus disease (EVD)
and clinical management of EVD in settings outside West Africa, as well as the …

[HTML][HTML] Prognostic indicators for Ebola patient survival

SJ Crowe, MJ Maenner, S Kuah… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
RESEARCH consistently provide supportive care, but during the second 2 months, after the
unit was reorganized by a new management team, the unit did provide such care …

The use of Ebola convalescent plasma to treat Ebola virus disease in resource-constrained settings: a perspective from the field

J van Griensven, A De Weiggheleire… - Clinical Infectious …, 2016 - academic.oup.com
The clinical evaluation of convalescent plasma (CP) for the treatment of Ebola virus disease
(EVD) in the current outbreak, predominantly affecting Guinea, Sierra Leone, and Liberia …

A case of severe Ebola virus infection complicated by gram-negative septicemia

B Kreuels, D Wichmann, P Emmerich… - New england journal …, 2014 - Mass Medical Soc
Ebola virus disease (EVD) developed in a patient who contracted the disease in Sierra
Leone and was airlifted to an isolation facility in Hamburg, Germany, for treatment. During …

Evaluation of convalescent whole blood for treating Ebola Virus Disease in Freetown, Sierra Leone

F Sahr, R Ansumana, TA Massaquoi, BR Idriss… - Journal of Infection, 2017 - Elsevier
Background Convalescent blood therapy has been a promising form of treatment for Ebola
Virus Disease (EVD), but less attention has been focused on it for treatment. Method We …

Clinical presentation of patients with Ebola virus disease in Conakry, Guinea

EI Bah, MC Lamah, T Fletcher, ST Jacob… - … England Journal of …, 2015 - Mass Medical Soc
Background In March 2014, the World Health Organization was notified of an outbreak of
Zaire ebolavirus in a remote area of Guinea. The outbreak then spread to the capital …