Background Primary hyperoxaluria (PH) type 3 (PH3) is caused by mutations in the hydroxy-
oxo-glutarate aldolase 1 gene. PH3 patients often present with recurrent urinary stone …

Outcome data in primary hyperoxaluria type 3 (PH3), described as a less severe form of the
PH's with a low risk of chronic kidney disease, are scarce. To investigate this, we …

Background. Primary hyperoxaluria type 1 (PH1) is a phenotypically heterogeneous
disease. To date the relationship between biochemical parameters and outcome is unclear …

Abstract Background Primary hyperoxaluria Type 1, an inherited disorder with increased
endogenous oxalate production, leads to the development of urolithiasis, nephrocalcinosis …

Primary hyperoxaluria (PH) is a rare autosomal recessive disease characterized by oxalate
accumulation in the kidneys and other organs. Three loci have been identified: AGXT (PH1) …

Primary hyperoxaluria type 1 (PH1) is caused by a deficiency of the liver peroxisomal
enzyme alanine: glyoxylate-aminotransferase (AGT), which catalyzes the conversion of …

Primary hyperoxaluria (PH) is a group of genetic disorders that result in an increased
hepatic production of oxalate. PH type 3 (PH3) is the most recently identified subtype and …

Background and aim Primary hyperoxalurias are rare inborn errors of metabolism resulting
in increased endogenous production of oxalate that leads to excessive urinary oxalate …

Primary hyperoxaluria, types 1 and 2, are rare disorders. Much of the information in the
literature has been derived from case reports and data registries limited to patients requiring …

Primary hyperoxaluria is a rare monogenic disorder characterized by excessive hepatic
production of oxalate leading to recurrent nephrolithiasis, nephrocalcinosis, and progressive …