Increasing sample diversity in psychiatric genetics–Introducing a new cohort of patients with schizophrenia and controls from Vietnam–Results from a pilot study

VT Nguyen, A Braun, J Kraft, TMT Ta… - The World Journal of …, 2022 - Taylor & Francis
Abstract Objectives Genome-Wide Association Studies (GWAS) of Schizophrenia (SCZ)
have provided new biological insights; however, most cohorts are of European ancestry. As …

[HTML][HTML] Genome-wide association study of schizophrenia in Japanese population

K Yamada, Y Iwayama, E Hattori, K Iwamoto, T Toyota… - PloS one, 2011 - journals.plos.org
Schizophrenia is a devastating neuropsychiatric disorder with genetically complex traits.
Genetic variants should explain a considerable portion of the risk for schizophrenia, and …

GWAS‐identified schizophrenia risk SNPs at TSPAN18 are highly diverged between Europeans and East Asians

J Liu, M Li, B Su - American Journal of Medical Genetics Part B …, 2016 - Wiley Online Library
Genome‐wide association studies (GWASs) have identified multiple schizophrenia (SCZ)
risk variants for samples of European and East Asian descent, but most of the identified …

Polygenetic risk scores for major psychiatric disorders among schizophrenia patients, their first-degree relatives, and healthy participants

K Ohi, D Nishizawa, T Shimada… - International Journal …, 2020 - academic.oup.com
Background The genetic etiology of schizophrenia (SCZ) overlaps with that of other major
psychiatric disorders in samples of European ancestry. The present study investigated …

Evaluation of European schizophrenia GWAS loci in Asian populations via comprehensive meta-analyses

X Xiao, X Luo, H Chang, Z Liu, M Li - Molecular Neurobiology, 2017 - Springer
Schizophrenia is a severe and highly heritable neuropsychiatric disorder. Recent genetic
analyses including genome-wide association studies (GWAS) have implicated multiple …

[HTML][HTML] A commentary: Do specific gene risk variants for schizophrenia contribute similarly to the incidence of schizophrenia world-wide?

LE DeLisi - npj Schizophrenia, 2017 - nature.com
In the 1980s there was extensive debate as to whether schizophrenia exists to the same
extent in all cultures and geographic areas throughout the world (reviewed in ref. 1). While …

Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect

M Ikeda, A Takahashi, Y Kamatani… - Schizophrenia …, 2019 - academic.oup.com
Genome-wide association studies (GWASs) have identified> 100 susceptibility loci for
schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by …

Replication of Han Chinese GWAS loci for schizophrenia via meta-analysis of four independent samples

X Xiao, M Li - Schizophrenia research, 2016 - Elsevier
Schizophrenia is a highly heritable psychiatric disorder with unclear aetiology. Recent
genome-wide association studies (GWAS) in European populations have reported …

[HTML][HTML] Variability of 128 schizophrenia-associated gene variants across distinct ethnic populations

K Ohi, T Shimada, T Yasuyama, T Uehara… - Translational …, 2017 - nature.com
Schizophrenia is a common polygenetic disease affecting 0.5–1% of individuals across
distinct ethnic populations. PGC-II, the largest genome-wide association study investigating …

Genome-wide association study of multiplex schizophrenia pedigrees

DF Levinson, J Shi, K Wang, S Oh… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective The authors used a genome-wide association study (GWAS) of multiply affected
families to investigate the association of schizophrenia to common single-nucleotide …