A central tenet in the design of vaccines is the display of native-like antigens in the elicitation
of protective immunity. The abundance of N-linked glycans across the SARS-CoV-2 spike …

The structure and post-translational processing of the SARS-CoV-2 spike glycoprotein (S) is
intimately associated with the function of the virus and of sterilising vaccines. The surface of …

Extensive glycosylation of viral glycoproteins is a key feature of the antigenic surface of
viruses and yet glycan processing can also be influenced by the manner of their …

Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …

The emergence of SARS-CoV-2 variants alters the efficacy of existing immunity, whether
arisen naturally or through vaccination. Understanding the structure of the viral spike assists …

The emergence of the betacoronavirus, SARS-CoV-2 that causes COVID-19, represents a
significant threat to global human health. Vaccine development is focused on the principal …

The emergence of the betacoronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …

Severe acute respiratory syndrome coronavirus 2 is the causative pathogen of the COVID-
19 pandemic which as of March 29, 2021, has claimed 2 776 175 lives worldwide. Vaccine …

Coronaviruses hijack human enzymes to assemble the sugar coat on their spike
glycoproteins. The mechanisms by which human antibodies may recognize the antigenic …

The densely glycosylated spike (S) proteins that are highly exposed on the surface of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) facilitate viral attachment, entry …