Despite the advancement in the well-equipped and sophisticated laboratories and facilities,
cancer remains to be a major cause of death worldwide. Consequently, further investigation …

Cancer is one of the world's biggest healthcare burdens and despite the current
advancements made in treatment plans, the outcomes for oncology patients have yet to …

Celastrol is a highly investigated anticancer moiety. It is a pentacyclic triterpenoid, isolated
several decades ago with promising role in chemoprevention. Celastrol has been found to …

Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

Identification of active constituents and their molecular targets from traditional medicine is an
enormous opportunity for modern pharmacology. Celastrol is one such compound that was …

Human estrogen receptor α (ERα) is a nuclear transcription factor that displays a major
therapeutic target for breast cancer. The transcriptional activity of ERα can be regulated by …

Celastrol, a plant triterpene has attracted great interest recently, especially for its potential
anti-inflammatory and anti-cancer activities. In the present report, we investigated the effect …

Celastrol, a quinone methide triterpene, is a pharmacologically active compound present in
Thunder God Vine root extracts used as a remedy of inflammatory and autoimmune …

In the recent years, much attention has been focused on identifying bioactive compounds
from medicinal plants that could be employed in therapeutics, which is attributed to their …

Understanding the molecular basis and target of traditional medicine is critical for drug
development. Celastrol, derived from Trypterygium wilfordii Hook F.(“Thunder of God Vine”) …