Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple
genetic associations with such disorders, but better methods are needed to derive the …

The primary aim of precision medicine is to tailor healthcare more closely to the needs of
individual patients. This requires progress in two areas: the development of more precise …

The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of
psychiatry. This global effort is dedicated to rapid progress and open science, and in the …

Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …

Psychiatric genetics is in an era of discovery. Genome-wide association analyses and other
genomic analyses are paving the way for rapid progress in understanding the biological …

The human genome project has spurred great enthusiasm in many research communities
and, of special interest to readers of Biological Psychiatry, has raised hope that genetic …

Psychiatric Genomics presents and synthesizes available knowledge in the field of
psychiatric genomics, offering methodologies to advance new research and aid clinical …

Highlights•We summarize recent findings in psychiatric genomics and look ahead to
2015.•We pose three major challenges for the field over the coming 5 years.•We propose a …

Genome-wide association studies (GWAS) have been the focus of considerable effort in
psychiatry. These efforts have markedly increased knowledge of the genetic basis of …

Most neuropsychiatric disorders are highly polygenic, implicating hundreds to thousands of
causal genetic variants that span much of the genome. This widespread polygenicity …