Uromodulin, the most abundant protein in normal urine, is produced by cells lining the thick
ascending limb (TAL) of the loop of Henle. Uromodulin regulates the activity of the …

Uromodulin, the most abundant protein in normal urine, is essentially produced by the cells
lining the thick ascending limb. There it regulates the activity of the cotransporter NKCC2 …

The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in
kidney and cardiovascular research. Genome-wide association studies discovered variants …

Tamm-Horsfall glycoprotein (THGP) or Uromodulin is a membrane protein exclusively
expressed along the thick ascending limb (TAL) and early distal convoluted tubule (DCT) of …

Medullary cystic kidney disease/familial juvenile hyperuricemic nephropathy (MCKD/FJHN)
are autosomal dominant renal disorders characterized by tubulo‐interstitial fibrosis …

Uromodulin (Tamm–Horsfall protein) is the most abundant protein excreted in the urine
under physiological conditions. It is exclusively produced in the kidney and secreted into the …

Uromodulin (also known as Tamm-Horsfall protein) is exclusively produced in the kidney
and is the most abundant protein in normal urine. The function of uromodulin remains …

Background Uromodulin, the most abundant protein excreted in normal urine, plays major
roles in kidney physiology and disease. The mechanisms regulating the urinary excretion of …

The most abundant urinary protein, Tamm–Horsfall protein, later renamed uromodulin, is
expressed exclusively by the thick ascending limb cells of the kidney and released into urine …

Expression of Tamm-Horsfall protein (THP or uromodulin) is highly restricted to the kidney
thick ascending limb (TAL) of loop of Henle. Despite the unique location and recent …