Aging is characterized by the progressive deterioration of tissue structure and function,
leading to increased vulnerability to diseases and, eventually, death. One prominent …

Recent reports in oncological and non-oncological experimental setups provide strong
evidence that senescent cells are under the surveillance of CD8 T cell-mediated adaptive …

Age-associated changes in CD4 T-cell functionality have been linked to chronic
inflammation and decreased immunity. However, a detailed characterization of CD4 T cell …

As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic
expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of …

Mitigating effects of aging on human health remains elusive because aging impacts multiple
systems simultaneously, and because experimental animals exhibit critical aging differences …

Immune aging may underlie various aging-related disorders, including diminished
resistance to infection, chronic inflammatory disorders, and autoimmunity. PD-1+ and …

The aging process is accompanied by altered immune system functioning and an increased
risk of infection. Dendritic cells (DCs) are antigen-presenting cells that play a key role in both …

Aging leads to a progressive functional decline of the immune system, which renders the
elderly increasingly susceptible to disease and infection. The degree to which immune cell …

Supercentenarians, people who have reached 110 y of age, are a great model of healthy
aging. Their characteristics of delayed onset of age-related diseases and compression of …

In aged hosts, T cells turn traitorous | Science Translational Medicine news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in science science advances …