Objective The role of A1 adenosine receptors in preconditioning in humans is unknown. To
establish whether bamiphylline, a selective antagonist of A1 adenosine receptors, abolishes …

The ability of brief periods of ischaemia to protect the heart from subsequent ischaemia has
been termed 'ischaemic preconditioning'. In order to assess the role of adenosine receptor …

The increased tolerance to myocardial ischemia observed during the second of two
sequential exercise tests, ie the warm-up phenomenon, has been proposed as a clinical …

There is evidence that the first balloon inflation during coronary angioplasty provides a
preconditioning stimulus leading to decreased ischemia during subsequent balloon …

Background Experimental studies indicate that α-adrenergic receptors are involved in
ischemic preconditioning. Their role in humans is unknown. Methods and Results Eighteen …

Objective: The aim was to test the hypothesis that adenosine A1 receptor activation triggers
the cardioprotective effects of ischaemic preconditioning, by determining whether …

A variety of experimental studies have confirmed that preconditioning the myocardium by
brief periods of ischemia represents a powerful cardioprotective effect resulting in a …

Background It is unknown whether adenosine can precondition human myocardium against
ischemia in vivo. Methods and Results Thirty patients were randomized to receive a 10 …

Objective: The aims were to examine the role of adenosine receptors in the mechanism of
preconditioning in a chronic rabbit model of myocardial infarction; to assess whether the …

Objective: A preconditioning mimetic agent could be useful therapy for cardiac ischaemic
events; stimulation of adenosine receptors has been proposed as a preconditioning …