Early-onset colorectal cancer: initial clues and current views

LJ Hofseth, JR Hebert, A Chanda, H Chen… - Nature reviews …, 2020 - nature.com
Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

The role of diet and lifestyle in early-onset colorectal cancer: a systematic review

M Puzzono, A Mannucci, S Grannò, RA Zuppardo… - Cancers, 2021 - mdpi.com
Simple Summary This systematic review sifted through the exogenous dietary and lifestyle
risk factors associated with early-onset colorectal cancer, going through the putative …

Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or
women in the United States. Average-risk screening that begins at age 50 years has …

Risk factors for early-onset colorectal cancer: a systematic review and meta-analysis

DE O'Sullivan, RL Sutherland, S Town, K Chow… - Clinical …, 2022 - Elsevier
Background & Aims Despite the widespread increase in the incidence of early-onset
colorectal cancer (EoCRC), the reasons for this increase remain unclear. The objective of …

[HTML][HTML] Early-onset colorectal cancer: A review of current knowledge

MR Saraiva, I Rosa, I Claro - World journal of gastroenterology, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Although
most prevalent among older people, its incidence above 50 years old has been decreasing …

Risk factors for early-onset colorectal cancer: a population-based case–control study in Ontario, Canada

VC Chang, M Cotterchio, P De, J Tinmouth - Cancer causes & control, 2021 - Springer
Purpose There has been an alarming increase in colorectal cancer (CRC) incidence among
young adults aged< 50 years, and factors driving this upward trend are unknown. This study …

[HTML][HTML] Early-onset colorectal cancer: Current insights and future directions

CWK Wu, RN Lui - World journal of gastrointestinal oncology, 2022 - ncbi.nlm.nih.gov
Early-onset colorectal cancer (EOCRC) has seen an alarming rise worldwide over the past
two decades. The reason for this global trend is poorly understood. EOCRC appears to have …

Colorectal cancer in young adults

A Venugopal, EM Stoffel - Current treatment options in gastroenterology, 2019 - Springer
Purpose of review Routine screening for colorectal cancer (CRC) in adults> 50 years of age
has led to overall reductions in CRC incidence and CRC-related mortality. Yet CRC …