[HTML][HTML] Design of multiepitope vaccine candidate from a major capsid protein of the African swine fever virus

AB Rowaiye, AN Oli, MT Asala, EJ Nwonu, MO Njoku… - Veterinary Vaccine, 2023 - Elsevier
This study unveils immunodominant epitopes from the African Swine Fever Virus Major
Capsid protein and created a multiepitope vaccine candidate. Protein sequences of 42 …

[HTML][HTML] Immunoinformatics-based identification of highly conserved cytotoxic T-cell epitopes in polyprotein pp220 of African swine fever virus

AKA Juan, KMC Palma, MB Suarez… - Biomedical and …, 2022 - journals.lww.com
Background: High mortality rate of pigs peaked in 2020 due to the re-emergence of a deadly
African swine fever virus (ASFV) which has led to transcontinental outbreaks in Europe …

[HTML][HTML] In silico design and evaluation of a multi-epitope and multi-antigenic African swine fever vaccine

AKG Buan, NAL Reyes, RNB Pineda, PMB Medina - ImmunoInformatics, 2022 - Elsevier
Abstract African Swine Fever (ASF) is caused by a highly contagious and fatal hemorrhagic
virus, which in 2019 alone in Asia, has killed 8 million pigs with a devastating estimated …

[HTML][HTML] In silico analysis of highly conserved cytotoxic T-cell epitopes in the structural proteins of African swine fever virus

LRDM Herrera, EP Bisa - Veterinary World, 2021 - ncbi.nlm.nih.gov
Materials and Methods: The amino acid sequences of the structural proteins were retrieved
from the National Center for Biotechnology Information protein database. The sequences …

[HTML][HTML] Identification of potential CD8+ epitopes in pp62 polyprotein of African swine fever virus using computational immunology

MLC Galicia, DJM Morales, PGB Pogado… - …, 2023 - ncbi.nlm.nih.gov
The highly infectious African swine fever virus (ASFV) is currently the only known DNA
arbovirus within the Asfarviridae family which primarily infects domestic pigs and wild boars …

[HTML][HTML] Immunoinformatics-guided approach for designing a pan-proteome multi-epitope subunit vaccine against African swine fever virus

AM Simbulan, EC Banico, EMJS Sira… - Scientific Reports, 2024 - nature.com
Despite being identified over a hundred years ago, there is still no commercially available
vaccine for the highly contagious and deadly African swine fever virus (ASFV). This study …

[PDF][PDF] Contriving a multi-epitope vaccine against African swine fever utilizing immunoinformatics

OA Fagbohun, CO Aiki-Raji… - Preprint https://doi. org/10, 2022 - academia.edu
African swine fever (ASF), a highly fatal haemorrhagic viral disease of domestic pigs has
been ravaging swine industries in affected countries. Effective management of this malady is …

[HTML][HTML] Identification of a linear B-cell epitope on the African swine fever virus CD2v protein

J Song, M Wang, Y Du, B Wan, A Zhang… - International Journal of …, 2023 - Elsevier
African swine fever virus (ASFV) poses a serious threat to domestic pigs and wild boars,
which is responsible for substantial production and economic losses. A dominant ASFV …

[HTML][HTML] Computational analysis of African swine fever virus protein space for the design of an epitope-based vaccine ensemble

A Ros-Lucas, F Correa-Fiz, L Bosch-Camós… - Pathogens, 2020 - mdpi.com
African swine fever virus is the etiological agent of African swine fever, a transmissible
severe hemorrhagic disease that affects pigs, causing massive economic losses. There is …

[HTML][HTML] Advancement in the development of gene/protein-based vaccines against African swine fever virus

N Wang, P Huang, J Zhang, M Lin, X Lai, J Chen… - Current Research in …, 2024 - Elsevier
African swine fever (ASF) is a highly contagious acute hemorrhagic viral disease, with the
mortality rate of up to 100% in domestic pigs. In recent years, ASF outbreaks have caused …