The Front Cover shows collective vibrational motions of alpha-helices inside a protein.
Studying the vibrations allows connecting protein structure and function, and therefore …

Functions of protein molecules in nature are closely associated with their well‐defined three‐
dimensional structures and dynamics in body fluid. So far, many efforts have been made to …

In a crystalline state, the protein molecules often come in contact with each other (Protein
Data Bank, Berman et al., 2002). However, the native proteins realize their function mainly in …

A single-parameter harmonic Hamiltonian based on local packing density and contact
topology is proposed for studying residue fluctuations in native proteins. The internal energy …

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Low-frequency vibrations in biomacromolecules possess significant biological functions. In
this paper, the alpha-helix element is compared with a mass-distributed spring. Based on …

We mentioned in Chapter 2 that proteins are not static entities, but flexible macromolecules
able to change their three-dimensional conformation based on external conditions …

Adenosine triphosphate (ATP) is known to be the main energy currency of the living cell, and
is used as a coenzyme to generate energy for many cellular processes through hydrolysis to …

The internal dynamics of a 20-residue polyalanine helix was investigated by molecular
dynamics simulations. Special attention was paid to the collective vibrations of the helix …

Protein internal dynamics is crucial for its function. In particular, low-energy vibrational
modes at 1–10 meV play important roles in the transportation of energy inside the protein …