Concern regarding coronavirus (CoV) outbreaks has stayed relevant to global health in the
last decades. Emerging COVID-19 infection, caused by the novel SARS-CoV2, is now a …

Interferon (IFN) therapies are used to treat a variety of infections and diseases and could be
used to treat SARS-CoV-2. However, optimal use and timing of IFN therapy to treat SARS …

Interferon (IFN) has been highlighted in several randomized controlled trials as an attractive
therapeutic candidate based plausible mode of action, suppressed response in severe …

Severe acute respiratory syndrome coronavirus 2 principally weakens the hosts' innate
immune system by impairing the interferon function and production. Type I interferons (IFNs) …

The rapidly progressing of coronavirus disease 2019 (COVID-19) pandemic has become a
global concern. This meta-analysis aimed at evaluating the efficacy and safety of current …

The recently public health crises in the world is emerged by spreading the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) also named COVID-19. The virus is …

Abstract Type 1 Interferons (IFNs) have been associated with positive effects on
Coronaviruses. Previous studies point towards the superior potency of IFNβ compared to …

Interferons were repeatedly used in the therapy of COVID-19 due to their antiviral effects.
Three recently published randomized controlled clinical phase III trials (WHO SOLIDARITY …

Introduction IFN-α intervention may block SARS-CoV-2 replication and normalize the
deregulated innate immunity of COVID-19. Aim This meta-analysis aimed to investigate the …

Abstract Coronavirus disease 2019 (COVID-19) experienced an outbreak that expanded
worldwide. Lopinavir/ritonavir (LPV/r), which is used effectively for severe acute respiratory …