In addition to the traditional staging system in colorectal cancer (CRC), the Immunoscore®
has been proposed to characterize the level of immune infiltration in tumor tissue and as a …

There is growing evidence that the immune system may prevent the occurrence, growth and
metastatic diffusion of colorectal cancer (CRC). The role played by the adaptive immune …

Purpose The prognosis of patients with colorectal cancer has sometimes proved uncertain;
thus, the prognostic significance of immune criteria was compared with that of the tumor …

Purpose The aim of this study was to evaluate the Immunoscore (IS) methodology as a
prognostic marker of colorectal adenocarcinoma in Tunisian population. Tumor blocks were …

Simple Summary This work determines the predictive value of the consensus Immunoscore
in 1885 patients with AJCC/UICC-TNM stage I-II Colon Cancer (CC) from North American …

Background New and fully validated tests need to be brought into clinical practice to improve
the estimation of recurrence risk in patients with colon cancer. The aim of this study was to …

The past two decades witnessed the appreciation of the importance of specific tumor-
infiltrating immune cells in influencing tumor evolution. The discovery that a favorable …

Aims. Immunoscore, based on the evaluation of CD3+ and CD8+ densities in the center of
the tumor and its invasive margin, is currently considered as a potential prognostic factor …

3500 Background: Mounting evidence indicates an enhanced lymphocytic reaction as an
informative prognostic indicator in colon cancer (CC). The IM methodology has been defined …

Tumor-infiltrating immune cells, such as lymphocytes and macrophages, have been
associated with tumor aggressiveness, prognosis and treatment response in colorectal …