Heat shock proteins (HSPs) have been implicated in the stimulation and generation of both
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …

Heat shock proteins are abundant soluble intracellular proteins, present in all cells.
Members of the heat shock protein family bind peptides including antigenic peptides …

There has been growing evidence that heat-shock protein (HSP) functions as an
endogenous immunomodulator for innate and adaptive immune responses. Since HSPs …

Immunization with heat shock proteins (HSPs) induces Ag-specific CTL responses. The
specificity of the immune response is based on peptides associated with HSPs. To …

Heat-shock proteins (HSPs) are the most abundant and ubiquitous soluble intracellular
proteins. In single-cell organisms, invertebrates and vertebrates, they perform a multitude of …

The ability of heat shock proteins to (1) chaperone peptides, including antigenic peptides;(2)
interact with antigen-presenting cells through a receptor;(3) stimulate antigen-presenting …

Exogenously delivered antigenic peptides complexed to heat shock proteins (HSPs) are
able to enter the endogenous Ag-processing pathway and prime CD8+ CTL. It was …

Peptides bound or linked to heat-shock proteins (HSPs) of microbial or mammalian origin
have been shown to elicit potent antigen-specific immunity. Some members of the HSP …

Heat shock proteins (HSPs) have been described as potent tumor vaccines in animal
models and are currently studied in clinical trials. The underlying immune response relies on …

Recently, growing evidences that extracellular heat shock protein (HSP) functions as
endogenous immunomodulator for innate and adaptive immune responses have been …