Various DNA repair pathways protect the structural and chemical integrity of the human
genome from environmental and endogenous threats. Polymorphisms of genes encoding …

Background: DNA repair is one of the crucial defense mechanism against mutagenic
exposure. Inherited SNPs of DNA repair genes may contribute to variation in DNA repair …

ABSTRACT DNA repair is one of the central defense mechanisms against mutagenic
exposures. Inherited SNPs of DNA repair genes may contribute to variations in DNA repair …

Reduction in DNA repair capacity is associated with increased rates of birth defects, cancer,
and accelerated ageing. Genetic polymorphisms in DNA repair genes might influence the …

DNA repair genes are crucial in maintaining the integrity of the whole genome. Single
nucleotide polymorphisms (SNPs) in DNA repair genes have been attributed to the …

Identifying risk factors for human cancers should consider combinations of genetic variations
and environmental exposures. Several polymorphisms in DNA repair genes have impact on …

DNA repair capacity is essential in maintaining cellular functions and homeostasis.
However, the repair capacity can be altered based on DNA sequence variations in DNA …

Background: Polymorphisms in DNA repair genes are associated with ability to remove DNA
lesions, and therefore may contribute to an individual's susceptibility to different types of …

Genetic polymorphisms in DNA repair genes might influence the repair activities of the
enzymes predisposing individuals to cancer risk. Owing to the presence of these genetic …

DNA repair systems play an important role in maintaining the integrity of the human genome.
Deficiency in the repair capacity due to either mutations or inherited polymorphisms in DNA …