Background After a single-center trial and observational studies suggesting that early, goal-
directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials …

Purpose To determine whether early goal-directed therapy (EGDT) reduces mortality
compared with other resuscitation strategies for patients presenting to the emergency …

Studies and meta-analyses conflict regarding the use of early goal-directed therapy (EGDT)
for septic shock. We sought to clarify the conflict by performing a living systematic review and …

Background Early, goal-directed therapy (EGDT) is recommended in international
guidelines for the resuscitation of patients presenting with early septic shock. However …

Objective To determine the clinical effectiveness of implementing early goal-directed therapy
(EGDT) as a routine protocol in the emergency department (ED). Methods Prospective …

Objective Early goal-directed therapy (EGDT) has been shown to decrease mortality in
patients with severe sepsis and septic shock. Consensus guidelines now advocate EGDT for …

Background Early goal-directed therapy (EGDT) has been endorsed in the guidelines of the
Surviving Sepsis Campaign as a key strategy to decrease mortality among patients …

Background In a single-center study published more than a decade ago involving patients
presenting to the emergency department with severe sepsis and septic shock, mortality was …

Background Early goal-directed therapy (EGDT) has been endorsed in the guidelines of the
Surviving Sepsis Campaign as a key strategy to decrease mortality among patients …

Severe sepsis and septic shock are among the leading causes of mortality in the intensive
care unit. Over a decade ago, early goal-directed therapy (EGDT) emerged as a novel …