[HTML][HTML] Affinity-restricted memory B cells dominate recall responses to heterologous flaviviruses

R Wong, JA Belk, J Govero, JL Uhrlaub, D Reinartz… - Immunity, 2020 - cell.com
Memory B cells (MBCs) can respond to heterologous antigens either by molding new
specificities through secondary germinal centers (GCs) or by selecting preexisting clones …

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

WE Purtha, TF Tedder, S Johnson… - Journal of Experimental …, 2011 - rupress.org
Memory B cells (MBCs) and long-lived plasma cells (LLPCs) persist after clearance of
infection, yet the specific and nonredundant role MBCs play in subsequent protection is …

Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells

WAA Saron, APS Rathore, L Ting, EE Ooi, J Low… - Science …, 2018 - science.org
How previous immunity influences immune memory recall and protection against related
flaviviruses is largely unknown, yet encounter with multiple flaviviruses in a lifetime is …

[HTML][HTML] Restricted clonality and limited germinal center reentry characterize memory B cell reactivation by boosting

L Mesin, A Schiepers, J Ersching, A Barbulescu… - Cell, 2020 - cell.com
Repeated exposure to pathogens or their antigens triggers anamnestic antibody responses
that are higher in magnitude and affinity than the primary response. These involve …

[HTML][HTML] Generation of high quality memory B cells

T Inoue, R Shinnakasu, T Kurosaki - Frontiers in immunology, 2022 - frontiersin.org
Protection against pathogen re-infection is mediated, in large part, by two humoral cellular
compartments, namely, long-lived plasma cells and memory B cells. Recent data have …

Memory B cells

T Inoue, T Kurosaki - Nature Reviews Immunology, 2024 - nature.com
Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

Recall of B cell memory depends on relative locations of prime and boost immunization

M Kuraoka, CH Yeh, G Bajic, R Kotaki, S Song… - Science …, 2022 - science.org
Immunization or microbial infection can establish long-term B cell memory not only
systemically but also locally. Evidence has suggested that local B cell memory contributes to …

[HTML][HTML] Remembrance of things past: long-term B cell memory after infection and vaccination

AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …

Generation of memory B cells and their reactivation

T Inoue, I Moran, R Shinnakasu, TG Phan… - Immunological …, 2018 - Wiley Online Library
The successful establishment of humoral memory response depends on at least two layers
of defense. Pre‐existing protective antibodies secreted by long‐lived plasma cells act as a …

Memory B cells

T Kurosaki, K Kometani, W Ise - Nature Reviews Immunology, 2015 - nature.com
The immune system can remember a previously experienced pathogen and can evoke an
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …