The faecal metabolome in COVID-19 patients is altered and associated with clinical features and gut microbes

L Lv, H Jiang, Y Chen, S Gu, J Xia, H Zhang, Y Lu… - Analytica chimica …, 2021 - Elsevier
Although SARS-CoV-2 can invade the intestine, though its effect on digestion and
absorption is not fully understood. In the present study, 56 COVID-19 patients and 47 age …

Fecal multi-omics analysis reveals diverse molecular alterations of gut ecosystem in COVID-19 patients

F He, T Zhang, K Xue, Z Fang, G Jiang, S Huang… - Analytica chimica …, 2021 - Elsevier
Gut ecosystem has profound effects on host physiology and health. Gastrointestinal (GI)
symptoms were frequently observed in patients with COVID-19. Compared with other …

Metabolomics study of COVID-19 patients in four different clinical stages

A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …

Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and …

D Zhang, S Weng, C Xia, Y Ren, Z Liu, Y Xu, X Yang… - BMC medicine, 2023 - Springer
Background Since the coronavirus disease 2019 (COVID-19) outbreak, many COVID-19
variants have emerged, causing several waves of pandemics and many infections. Long …

The serum metabolome of COVID-19 patients is distinctive and predictive

D Shi, R Yan, L Lv, H Jiang, Y Lu, J Sheng, J Xie, W Wu… - Metabolism, 2021 - Elsevier
Background Metabolism is critical for sustaining life, immunity and infection, but its role in
COVID-19 is not fully understood. Methods Seventy-nine COVID-19 patients, 78 healthy …

The serum metabolome of moderate and severe COVID-19 patients reflects possible liver alterations involving carbon and nitrogen metabolism

M Caterino, M Costanzo, R Fedele, A Cevenini… - International Journal of …, 2021 - mdpi.com
COVID-19 is a global threat that has spread since the end of 2019, causing severe clinical
sequelae and deaths, in the context of a world pandemic. The infection of the highly …

Metabolomics markers of COVID-19 are dependent on collection wave

HM Lewis, Y Liu, CF Frampas, K Longman, M Spick… - Metabolites, 2022 - mdpi.com
The effect of COVID-19 infection on the human metabolome has been widely reported, but to
date all such studies have focused on a single wave of infection. COVID-19 has generated …

Metabolic signatures associated with severity in hospitalized COVID-19 patients

J Marín-Corral, J Rodríguez-Morató… - International journal of …, 2021 - mdpi.com
The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the
metabolic pathways that are altered early with viral infection and their association with …

Metabolite profile of COVID-19 revealed by UPLC-MS/MS-based widely targeted metabolomics

J Liu, ZB Li, QQ Lu, Y Yu, SQ Zhang, PF Ke… - Frontiers in …, 2022 - frontiersin.org
The metabolic characteristics of COVID-19 disease are still largely unknown. Here, 44
patients with COVID-19 (31 mild COVID-19 patients and 13 severe COVID-19 patients), 42 …

Characterization of oral and gut microbiome and plasma metabolomics in COVID-19 patients after 1-year follow-up

GY Cui, BC Rao, ZH Zeng, XM Wang, T Ren… - Military Medical …, 2022 - Springer
Background Due to the outbreak and rapid spread of coronavirus disease 2019 (COVID-19),
more than 160 million patients have become convalescents worldwide to date. Significant …