The natural compound Artemisinin is the most widely used antimalarial drug worldwide.
Based on its cytotoxicity, it is also used for anticancer therapy. Artemisinin and its derivates …

Secondary metabolites from plants can serve as defense against herbivores, microbes,
viruses or competing plants. Many compounds from medicinal plants have pharmacological …

Artemisinin derivatives are well-tolerated anti-malaria drugs that also exert anti-cancer
activity. Here, we investigated artemisinin and its derivatives dihydroartemisinin and …

Artemisinin and its derivatives (collectively termed as artemisinins) are among the most
important and effective antimalarial drugs, with proven safety and efficacy in clinical use …

Secondary metabolites from plants serve as defense against herbivores, microbes, viruses,
or competing plants. Many medicinal plants have pharmacological activities and may, thus …

In addition to their well-known anti-malarial activity, artemisinin and its derivatives (1, 2, 4-
trioxanes) possess potent activity against tumor cells in the nano-to micromolar range …

The antimalarial artemisinin (ART) possesses anticancer activity, but its underlying
mechanism remains largely unclear. Using a chemical proteomics approach with artemisinin …

Artemisinin and its derivatives (ARTs) are effective antimalarial drugs and also possess
profound anticancer activity. However, the mechanism accounted for its distinctive activity in …

The world is experiencing a cancer epidemic and an increase in the prevalence of the
disease. Cancer remains a major killer, accounting for more than half a million deaths …

The majority of drug candidates fails the approval phase due to unwanted toxicities and side
effects. Establishment of an effective toxicity prediction platform is of utmost importance, to …