Endocytosis of BRASSINOSTEROID INSENSITIVE1 is partly driven by a canonical Tyr-based motif

D Liu, R Kumar, LAN Claus, AJ Johnson, W Siao… - Plant Cell, 2020 - academic.oup.com
Clathrin-mediated endocytosis (CME) and its core endocytic machinery are evolutionarily
conserved across all eukaryotes. In mammals, the heterotetrameric adaptor protein complex …

The Clathrin Adaptor Complex AP-2 Mediates Endocytosis of BRASSINOSTEROID INSENSITIVE1 in Arabidopsis

S Di Rubbo, NG Irani, SY Kim, ZY Xu, A Gadeyne… - The Plant …, 2013 - academic.oup.com
Clathrin-mediated endocytosis (CME) regulates many aspects of plant development,
including hormone signaling and responses to environmental stresses. Despite the …

BRASSINOSTEROID INSENSITIVE1 internalization can occur independent of ligand binding

LA Neubus Claus, D Liu, U Hohmann… - Plant …, 2023 - academic.oup.com
The brassinosteroid (BR) hormone and its plasma membrane (PM) receptor BR
INSENSITIVE1 (BRI1) are one of the best-studied receptor–ligand pairs for understanding …

Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination

J Zhou, D Liu, P Wang, X Ma, W Lin… - Proceedings of the …, 2018 - National Acad Sciences
Plants largely rely on plasma membrane (PM)-resident receptor-like kinases (RLKs) to
sense extracellular and intracellular stimuli and coordinate cell differentiation, growth, and …

SUMO/deSUMOylation of the BRI1 brassinosteroid receptor modulates plant growth responses to temperature

M Naranjo-Arcos, M Srivastava… - Proceedings of the …, 2023 - National Acad Sciences
Brassinosteroids (BRs) are a class of steroid molecules perceived at the cell surface that act
as plant hormones. The BR receptor BRASSINOSTEROID INSENSITIVE1 (BRI1) offers a …

Spatiotemporal dynamics of the BRI1 receptor and its regulation by membrane microdomains in living Arabidopsis cells

L Wang, H Li, X Lv, T Chen, R Li, Y Xue, J Jiang, B Jin… - Molecular plant, 2015 - cell.com
The major brassinosteroid (BR) receptor of Arabidopsis BRASSINOSTEROID
INSENSITIVE1 (BRI1) plays fundamental roles in BR signaling, but the molecular …

Fluorescent castasterone reveals BRI1 signaling from the plasma membrane

NG Irani, S Di Rubbo, E Mylle, J Van den Begin… - Nature chemical …, 2012 - nature.com
Receptor-mediated endocytosis is an integral part of signal transduction as it mediates
signal attenuation and provides spatial and temporal dimensions to signaling events. One of …

Methylation of a phosphatase specifies dephosphorylation and degradation of activated brassinosteroid receptors

G Wu, X Wang, X Li, Y Kamiya, MS Otegui, J Chory - Science signaling, 2011 - science.org
Internalization of cell surface receptors, followed by either recycling back to the plasma
membrane or degradation, is crucial for receptor homeostasis and signaling. The plant …

BRS1, a serine carboxypeptidase, regulates BRI1 signaling in Arabidopsis thaliana

J Li, KA Lease, FE Tax… - Proceedings of the …, 2001 - National Acad Sciences
Brassinosteroid-insensitive 1 (BRI1) of Arabidopsis thaliana encodes a cell surface receptor
for brassinosteroids. Mutations in BRI1 severely affect plant growth and development …

Intragenic suppression of a trafficking-defective brassinosteroid receptor mutant in Arabidopsis

Y Belkhadir, A Durbak, M Wierzba, RJ Schmitz… - Genetics, 2010 - academic.oup.com
The cell surface receptor kinase BRASSINOSTEROID-INSENSITIVE-1 (BRI1) is the major
receptor for steroid hormones in Arabidopsis. Plants homozygous for loss-of-function …