Because modern humans originated in Africa and have adapted to diverse environments,
African populations have high levels of genetic and phenotypic diversity. Thus, genomic …

Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

Genetic variation and susceptibility to disease are shaped by human demographic history
and adaptation. We can now study the genomes of extant Africans and uncover traces of …

Since the completion of the human genome sequencing project, the discovery and
characterization of human genetic variation is a principal focus for future research …

Africa is the birthplace of modern humans, and is the source of the geographic expansion of
ancestral populations into other regions of the world. Indigenous Africans are characterized …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

Modern human genetic diversity is the result of demographic history, and selective effects
that have acted to adapt different populations to their environments. Broad patterns of global …

Africa is one of the most ethnically and genetically diverse regions of the world. It is thought
to be the ancestral homeland of all modern humans, and is the homeland of millions of …

The continent of Africa is thought to be the site of origin of all modern humans and is the
more recent origin of millions of African Americans. Although Africa has the highest levels of …

The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …