Currently, amino-terminal PEGylated human granulocyte colony stimulating factor (huG-
CSF) is used to prevent and treat neutropenia. Although huG-CSF has been used as a drug …

Granulocyte colony-stimulating factor (G-CSF) has found widespread clinical application,
and modified forms with improved biopharmaceutical properties have been marketed as …

Granulocyte colony-stimulating factor (G-CSF) is a 19 kDa glycoprotein that stimulates the
proliferation, maturation and functional activation of cells of the granulocyte lineage …

Recombinant human granulocyte colony stimulating factor (rhG-CSF) and its PEGylated
product “mono-PEG20-GCSF” have already been widely used for treatment of all kinds of …

Human granulocyte colony-stimulating factor (GCSF) is a well-known cytokine for
neutropenia treatment. However, daily injections are required due to the short circulating …

Granulocyte–macrophage colony-stimulating factor (GM-CSF) regulates proliferation,
differentiation, and function of hematopoietic progenitor cells. Aside from expansion of …

Abstract Mono PEGylated rhG-CSF (PEG-G-CSF) prepared by utilizing unique PEG was
purified and characterized by cation-exchange chromatography. A unique, trimer-structured …

In this study, the pharmacokinetic and pharmacodynamic properties of Lys 35, Met N-
terminal, and Lys 17-mono-PEGylated recombinant human granulocyte colony stimulating …

Context: Granulocyte colony stimulating factor (G-CSF) has been commonly used to treat
neutropenia caused by chemotherapy, radiotherapy, and organ transplants. Improved in …

Granulocyte colony-stimulating factor (G-CSF) is a cytokine secreted by stromal cells and
plays a role in the differentiation of bone marrow stem cells and proliferation of neutrophils …