Vitamin K plasma levels determination in human health

M Fusaro, M Gallieni, MA Rizzo, A Stucchi… - Clinical Chemistry and …, 2017 - degruyter.com
Vitamin K (phylloquinone or vitamin K1 and menaquinones or vitamin K2) plays an
important role as a cofactor in the synthesis of hepatic blood coagulation proteins, but …

Quantitative determination of plasma vitamin K1 by high-performance liquid chromatography coupled to isotope dilution tandem mass spectrometry

V Ducros, M Pollicand, F Laporte, A Favier - Analytical biochemistry, 2010 - Elsevier
Plasma vitamin K1 (phylloquinone) determination is commonly used for the diagnosis of
vitamin K deficiency in patients suffering from lipid malabsorption. Moreover, current …

Determination of vitamin K1 in plasma by solid phase extraction and HPLC with fluorescence detection

R Paroni, EM Faioni, C Razzari, G Fontana… - … of Chromatography B, 2009 - Elsevier
We describe a procedure for quantification of vitamin K1 in human plasma by HPLC.
Samples, enriched with a vitamin K derivative as internal standard, were deproteinized …

Determination of plasma Vitamin K by high-performance liquid chromatography with fluorescence detection using Vitamin K analogs as internal standards

M Kamao, Y Suhara, N Tsugawa, T Okano - Journal of Chromatography B, 2005 - Elsevier
A HPLC fluorescence determination method for Vitamin K derivatives (Vitamin K1,
phylloquinone, PK and K2, menaquinones, MK-4 and MK-7) using post-column reduction …

Method for the determination of vitamin K homologues in human plasma using high-performance liquid chromatography-tandem mass spectrometry

Y Suhara, M Kamao, N Tsugawa, T Okano - Analytical chemistry, 2005 - ACS Publications
We report here the development of a precise and sensitive method for the determination of
vitamin K homologues including phylloquinone (PK), menaquinone-4 (MK-4), and …

A concise review of quantification methods for determination of vitamin K in various biological matrices

Y Zhang, V Bala, Z Mao, YS Chhonker… - Journal of pharmaceutical …, 2019 - Elsevier
Vitamin K is an essential nutrient in the body and involved in numerous physiological and
pathophysiological functions. Both the lack and surplus of vitamin K can put human health at …

HPLC Method for Plasma Vitamin K1: Effect of Plasma Triglyceride and Acute-Phase Response on Circulating Concentrations

MK Azharuddin, DSJ O'Reilly, A Gray… - Clinical …, 2007 - academic.oup.com
Background: The plasma concentration of vitamin K1 (phylloquinone) is the most reliable
index for assessing vitamin K status. Our aim was to analytically validate an HPLC method …

Simultaneous determination of vitamin K analogs in human serum by sensitive and selective high-performance liquid chromatography with electrochemical detection

H Wakabayashi, K Onodera, S Yamato, K Shimada - Nutrition, 2003 - Elsevier
OBJECTIVES: We report a sensitive and selective method for the simultaneous
determination of vitamin K1 and K2 analogs (VKs) with high-performance liquid …

Determination of vitamin K homologues by high-performance liquid chromatography with on-line photoreactor and peroxyoxalate chemiluminescence detection

S Ahmed, N Kishikawa, K Nakashima, N Kuroda - Analytica chimica acta, 2007 - Elsevier
A sensitive and highly selective high-performance liquid chromatography (HPLC) method
was developed for the determination of vitamin K homologues including phylloquinone (PK) …

Determination of phylloquinone (vitamin K1) in plasma and serum by HPLC with fluorescence detection

LY Wang, CJ Bates, L Yan, DJ Harrington… - Clinica chimica acta, 2004 - Elsevier
A modified high-performance liquid chromatography (HPLC) method, based on Davidson
and Sadowski [Meth. Enzymol. 282 (1997) 408], with fluorescence detection after zinc …