The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors

YQ Qian, M Billeter, G Otting, M Müller, WJ Gehring… - Cell, 1989 - cell.com
The structure of the Antennapedia homeodomain from Drosophila melanogaster was
determined by nuclear magnetic resonance spectroscopy in solution. It includes three well …

Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix‐turn‐helix motif.

G Otting, YQ Qian, M Müller, M Affolter… - The EMBO …, 1988 - embopress.org
The homeodomain encoded by the Antennapedia (Antp) gene of Drosophila was studied in
aqueous solution by nuclear magnetic resonance (NMR). Sequence‐specific resonance …

Determination of the three-dimensional structure of theAntennapedia homeodomain fromDrosophila in solution by1H nuclear magnetic resonance spectroscopy

M Billeter, Y Qian, G Otting, M Mu, WJ Gehring… - Journal of molecular …, 1990 - Elsevier
The determination of the three-dimensional structure of theAntennapedia homeodomain
fromDrosophila in solution is described. The techniques used are 1H nuclear magnetic …

Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent

D Derossi, S Calvet, A Trembleau, A Brunissen… - Journal of Biological …, 1996 - ASBMB
We have recently reported that a 16-amino acid long polypeptide corresponding to the third
helix of the DNA binding domain (homeodomain) of Antennapedia, a Drosophila …

Isolation and sequence‐specific DNA binding of the Antennapedia homeodomain.

M Müller, M Affolter, W Leupin, G Otting… - The EMBO …, 1988 - embopress.org
The homeodomain encoded by the Antennapedia (Antp) gene of Drosophila was
overproduced in a T7 expression vector in Escherichia coli. The corresponding polypeptide …

Homeobox genes and axial patterning

W McGinnis, R Krumlauf - Cell, 1992 - Elsevier
Animal embryos need to specify different cell types, and the genetic functions that provide
such controls are easy to comprehend since they result in the formation of overtly …

DNA binding properties of the purified Antennapedia homeodomain.

M Affolter, A Percival-Smith, M Müller… - Proceedings of the …, 1990 - National Acad Sciences
The in vitro DNA binding properties of a purified 68-amino acid Antennapedia
homeodomain (Antp HD) peptide have been analyzed. Equilibrium and kinetic binding …

Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain

YQ Qian, K Furukubo-Tokunaga… - Journal of molecular …, 1994 - Elsevier
The three-dimensional structure of a recombinant 70-residue polypeptide containing the
complete fushi tarazu (ftz) homeodomain from Drosophila melanogaster has been …

Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster.

S Schneuwly, A Kuroiwa, P Baumgartner… - The EMBO …, 1986 - embopress.org
The structure of the Drosophila melanogaster Antennapedia (Antp) gene has been
investigated by the isolation and sequencing of different cDNAs and genomic clones …

[PDF][PDF] Understanding the homeodomain.

TB Kornberg - Journal of Biological Chemistry, 1993 - scvrb-core.ucsf.edu
The homeotic genes of Drosophila have long captured the fascination of biologists, in part
for the remarkable phenotypes that mutant animals display. Homeotic mutants are capable …