One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from Streptomyces cacaoi CA …
F Román-Hurtado, M Sánchez-Hidalgo, J Martín… - Microorganisms, 2021 - mdpi.com
The strain Streptomyces cacaoi CA-170360 produces the cyclic pentapeptides
pentaminomycins A–H and BE-18257 A–C, two families of cyclopeptides synthesized by two …
pentaminomycins A–H and BE-18257 A–C, two families of cyclopeptides synthesized by two …
Pentaminomycins F and G, Nonribosomal Peptides Containing 2-Pyridylalanine
D Carretero-Molina, FJ Ortiz-López… - Journal of Natural …, 2021 - ACS Publications
Pentaminomycins F–H (1–3), a group of three new hydroxyarginine-containing cyclic
pentapeptides, were isolated from cultures of a Streptomyces cacaoi subsp. cacaoi strain …
pentapeptides, were isolated from cultures of a Streptomyces cacaoi subsp. cacaoi strain …
Pristinamycin I biosynthesis in Streptomyces pristinaespiralis: molecular characterization of the first two structural peptide synthetase genes
V de Crécy-Lagard, V Blanc, P Gil, L Naudin… - Journal of …, 1997 - Am Soc Microbiol
Two genes involved in the biosynthesis of the depsipeptide antibiotics pristinamycins I (PI)
produced by Streptomyces pristinaespiralis were cloned and sequenced. The 1.7-kb snbA …
produced by Streptomyces pristinaespiralis were cloned and sequenced. The 1.7-kb snbA …
Isolation and structure determination of a new antibacterial peptide pentaminomycin C from Streptomyces cacaoi subsp. cacaoi
I Kaweewan, H Hemmi, H Komaki, S Kodani - The Journal of Antibiotics, 2020 - nature.com
A new antibacterial peptide named pentaminomycin C was isolated from an extract of
Streptomyces cacaoi subsp. cacaoi NBRC 12748T, along with a known peptide BE-18257A …
Streptomyces cacaoi subsp. cacaoi NBRC 12748T, along with a known peptide BE-18257A …
Chemo-and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from …
J Grünewald, SA Sieber, MA Marahiel - Biochemistry, 2004 - ACS Publications
Here we report the first biochemical characterization of a recombinant nonribosomal peptide
cyclase of a streptomycete, the model actinomycete Streptomyces coelicolor A3 (2). This …
cyclase of a streptomycete, the model actinomycete Streptomyces coelicolor A3 (2). This …
Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster
The GE81112 tetrapeptides (1–3) represent a structurally unique class of antibiotics, acting
as specific inhibitors of prokaryotic protein synthesis. Here we report the cloning and …
as specific inhibitors of prokaryotic protein synthesis. Here we report the cloning and …
Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria
JAV Blodgett, DC Oh, S Cao… - Proceedings of the …, 2010 - National Acad Sciences
A combination of small molecule chemistry, biosynthetic analysis, and genome mining has
revealed the unexpected conservation of polycyclic tetramate macrolactam biosynthetic loci …
revealed the unexpected conservation of polycyclic tetramate macrolactam biosynthetic loci …
Novel compounds produced by Streptomyces lydicus NRRL 2433 engineered mutants altered in the biosynthesis of streptolydigin
C Gómez, C Olano, M Palomino-Schätzlein… - The Journal of …, 2012 - nature.com
Streptolydigin is a tetramic acid antibiotic produced by Streptomyces lydicus NRRL 2433
and involving a hybrid polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) …
and involving a hybrid polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) …
Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene
V de Crécy-Lagard, W Saurin, D Thibaut… - Antimicrobial agents …, 1997 - Am Soc Microbiol
Streptomyces pristinaespiralis and S. virginiae both produce closely related
hexadepsipeptide antibiotics of the streptogramin B family. Pristinamycins I and …
hexadepsipeptide antibiotics of the streptogramin B family. Pristinamycins I and …
Identification of pyrroloindoline-containing cyclic hexapeptides in the metabolites of Streptomyces alboflavus 313 by HPLC-DAD-ESI-MS/MS
Z Ji, N Xu, Q Gang, S Wei - The Journal of Antibiotics, 2013 - nature.com
To investigate the chemical biodiversity of biologically active cyclic hexapeptides in the
metabolites from microorganisms, the fermentation broth of Streptomyces alboflavus 313 …
metabolites from microorganisms, the fermentation broth of Streptomyces alboflavus 313 …