F Heller, A Fromm, AH Gitter, J Mankertz… - Mucosal …, 2008 - Elsevier
In ulcerative colitis, the T helper type 2 proinflammatory cytokine Interleukin-13 (IL-13) contributes as effector cytokine to the epithelial changes associated with disturbed epithelial …
PJ Mannon, RL Hornung, Z Yang, C Yi, C Groden… - Gut, 2011 - gut.bmj.com
Objective Ulcerative colitis is associated with increased interleukin 13 (IL-13) production by natural killer T cells. Taking advantage of the inhibitory actions of interferon β on IL-13 …
JM Leung, M Davenport, MJ Wolff, KE Wiens… - Mucosal …, 2014 - nature.com
T helper type (Th17) cytokines such as interleukin (IL)-17A and IL-22 are important in maintaining mucosal barrier function and may be important in the pathogenesis of …
P Biancheri, A Di Sabatino… - European journal of …, 2014 - Wiley Online Library
IL‐13 has been implicated in the pathogenesis of ulcerative colitis (UC), and may have a role in animal models of gut fibrosis. We studied the involvement of IL‐13 in inflammation …
G Bamias, G Kaltsa, SD Ladas - Discovery medicine, 2011 - discoverymedicine.com
Ulcerative colitis is a chronic inflammatory condition of the large intestine whose etiology remains largely unknown. Its pathogenesis involves the breakdown of intestinal mucosal …
V Hölttä, P Klemetti, T Sipponen… - Inflammatory bowel …, 2008 - academic.oup.com
Background We studied the balance between ileal T-effector cells versus T-regulatory cells in active and inactive Crohn's disease (CD). Methods We compared effector and regulatory …
S Inoue, T Matsumoto, M Iida, M Mizuno… - Official journal of the …, 1999 - journals.lww.com
OBJECTIVE: Mucosal inflammation in ulcerative colitis (UC) is presumed to be regulated by Th2-like cytokines. The aim of this study was to characterize local expression of various …
S Melgar, MMW Yeung, A Bas… - Clinical & …, 2003 - academic.oup.com
Ulcerative colitis (UC), a chronic inflammatory bowel disease, exhibits pronounced increase of T lymphocytes in the inflamed mucosa. To understand the role of intestinal T lymphocytes …
I Kirman, OH Nielsen - American Journal of …, 1996 - search.ebscohost.com
Abstract Objectives: Interleukin-15 (IL-15) is a novel cytokine sharing many of the activities of IL-2. The goal of this study was to evaluate intracellular and serum IL-15 in ulcerative colitis …