Polarity-dependent effect of low-frequency stimulation on amygdaloid kindling in rats

Z Xu, Y Wang, M Jin, J Yue, C Xu, X Ying, D Wu… - Brain stimulation, 2013 - Elsevier
BACKGROUND: Low-frequency stimulation (LFS,< 5 Hz) has been proposed as an
alternative option for the treatment of epilepsy. The stimulation pole, anode and cathode …

[HTML][HTML] Comparing the anticonvulsant effects of low frequency stimulation of different brain sites on the amygdala kindling acquisition in rats

K Esmaeilpour, Y Masoumi-Ardakani… - Basic and clinical …, 2013 - ncbi.nlm.nih.gov
Low frequency stimulation (LFS) is a potential alternative therapy for epilepsy. However, it
seems that the anticonvulsant effects of LFS depend on its target sites in the brain. Thus, the …

Time-dependent effect of low-frequency stimulation on amygdaloid-kindling seizures in rats

DC Wu, ZH Xu, S Wang, QI Fang, DQ Hu, Q Li… - Neurobiology of …, 2008 - Elsevier
Low-frequency stimulation (LFS) has been considered as a new option for the treatment of
intractable epilepsy. The present study was designed to determine whether LFS of the …

Consecutive 15 min is necessary for focal low frequency stimulation to inhibit amygdaloid-kindling seizures in rats

Y Liu, Y Wang, Z Xu, C Xu, X Ying, S Wang, S Zhang… - Epilepsy research, 2013 - Elsevier
Low-frequency stimulation (LFS) is emerging as a new option for the treatment of intractable
epilepsy. The stimulation duration may influence the anti-epileptic effect of LFS but is poorly …

Preemptive low‐frequency stimulation decreases the incidence of amygdala‐kindled seizures

JH Goodman, RE Berger, TK Tcheng - Epilepsia, 2005 - Wiley Online Library
Purpose: The use of electrical stimulation as a therapy for epilepsy is currently being studied
in experimental animals and in patients with epilepsy. This study examined the effect of …

Low-frequency stimulation of the kindling focus delays basolateral amygdala kindling in immature rats

L Velı́šek, J Velı́šková, PK Stanton - Neuroscience letters, 2002 - Elsevier
Stimulation of deep brain sites is a new approach for treatment of intractable seizures. In
adult rats, low-frequency stimulation (LFS; 1–3 Hz) of the kindling site interferes with the …

Low frequency stimulation modifies receptor binding in rat brain

ML Lopez-Meraz, L Neri-Bazan, L Rocha - Epilepsy research, 2004 - Elsevier
Experiments were designed to reproduce the antiepileptic effects of low frequency
stimulation (LFS) during the amygdala kindling process and to examine LFS-induced …

Combined sub-threshold dosages of phenobarbital and low-frequency stimulation effectively reduce seizures in amygdala-kindled rats

A Asgari, S Semnanian, N Atapour, A Shojaei… - Neurological …, 2014 - Springer
Low-frequency stimulation (LFS) is a potential therapy utilized in patients who do not
achieve satisfactory control of seizures with pharmacological treatments. Here, we …

Low frequency electrical stimulation either prior to or after rapid kindling stimulation inhibits the kindling‐induced Epileptogenesis

M Jalilifar, A Yadollahpour, AA Moazedi… - BioMed Research …, 2017 - Wiley Online Library
Objective. Studies are ongoing to find appropriate low frequency stimulation (LFS) protocol
for treatment of epilepsy. The present study aimed at assessing the antiepileptogenesis …

Effect of Focal Low‐frequency Stimulation on Amygdala‐kindled Afterdischarge Thresholds and Seizure Profiles in Fast‐and Slow‐kindling Rat Strains

CA Carrington, KL Gilby, DC McIntyre - Epilepsia, 2007 - Wiley Online Library
Purpose: To determine whether low‐frequency, 1‐Hz sine‐wave stimulation (LFS) applied to
a fully kindled amygdala focus would show antiepileptic properties in rats that were either …