An overview of the effect of linoleic and conjugated‐linoleic acids on the growth of several human tumor cell lines

M Maggiora, M Bologna, MP Cerù… - … journal of cancer, 2004 - Wiley Online Library
Abstract Both n‐6 and n‐3 polyunsaturated fatty acids are dietary fats important for cell
function, being involved in several physiologic and pathologic processes, such as …

Conjugated linoleic acid isomers and their conjugated derivatives inhibit growth of human cancer cell lines

A De La Torre, E Debiton, D Durand… - Anticancer …, 2005 - ar.iiarjournals.org
Conjugated linoleic acid (CLA), mainly c9, t11-and t10, c12-isomers, and polyunsaturated n-
3 fatty acids (n-3 PUFA) have been shown to reduce tumor growth. This study compared, on …

PPARγ‐dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF)

AM Cimini, L Cristiano, S Colafarina… - … Journal of Cancer, 2005 - Wiley Online Library
Conjugated linoleic acid (CLA) has been shown to exert beneficial effects against
carcinogenesis, atherosclerosis and diabetes. It has been demonstrated that CLA modulates …

Activation of PPARgamma may mediate a portion of the anticancer activity of conjugated linoleic acid

MF McCarty - Medical Hypotheses, 2000 - Elsevier
A number of human cancer cell lines express the PPARgamma transcription factor, and
agonists for PPARgamma are reported to promote apoptosis in these cell lines and impede …

PPARα and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK‐HEP‐1

G Muzio, M Maggiora, M Oraldi… - … journal of cancer, 2007 - Wiley Online Library
Conjugated linoleic acid (CLA), found in dairy products, in beef and lamb has been
demonstrated to possess anticancer properties protecting several tissues from developing …

Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat

C Ip, M Singh, HJ Thompson, JA Scimeca - Cancer research, 1994 - AACR
Conjugated linoleic acid (CLA) is a collective term which refers to a mixture of positional and
geometric isomers of linoleic acid. It is naturally occurring in meat and dairy products. We …

Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture.

TD Shultz, BP Chew, WR Seaman - Anticancer research, 1992 - europepmc.org
Consumption of dietary fat has been linked to the high incidence of certain cancers.
However, recent research has stimulated interest in conjugated linoleic acid (CLA), a newly …

Conjugated linoleic acids as anticancer nutrients: Studies in vivo and cellular mechanisms

S Banni, SD Heys, KWJ Wahle - Advances in conjugated linoleic …, 2020 - taylorfrancis.com
Conjugated linoleic acid (CLA) feeding affects different biological and biochemical
parameters in the mammary gland, which induce changes that render the mammary gland …

[HTML][HTML] Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n− 3 fatty acids

CJ Field, PD Schley - The American journal of clinical nutrition, 2004 - Elsevier
Conjugated linoleic acid (CLA) and the long-chain polyunsaturated n− 3 fatty acids have
been shown in vivo and in vitro to reduce tumor growth. Tumor growth could occur by …

Cell signal mechanisms, conjugated linoleic acids (CLAs) and anti-tumorigenesis

KWJ Wahle, SD Heys - Prostaglandins, leukotrienes and essential fatty …, 2002 - Elsevier
Fats have been adversely implicated in the aetiology of many forms of cancer yet evidence
is accumulating that certain types of fatty acids have anticancer properties. This is well …