Exosomes, small extracellular vesicles (EVs) with sizes of 30–150 nm, are formed by an
endosomal route and play a series of important roles in many physiological and pathological …

Introduction There are great potentials of using exosomal RNAs (exoRNA) as biomarkers in
cancers. The isolation of exoRNA requires the use of ultracentrifugation to isolate cell-free …

Almost all clinical oncologists agree that the discovery of reliable, accessible, and non-
invasive biomarkers is necessary to decrease cancer mortality. It is possible to employ …

Exosomes are endosome-derived extracellular vesicles that are released upon the fusion of
multivesicular bodies with the plasma membrane. These vesicles contain proteins, lipids …

Exosomes are considered as biomarkers reflecting the physiological state of the human
body. Studies have revealed that the expression levels of specific exosomal RNAs are …

Non-coding RNAs, such as microRNAs and long non-coding RNAs, are important regulatory
molecules which are corrupted in cancer, often in a tissue and stage specific manner …

Clinical oncologists need more reliable and non-invasive diagnostic and prognostic
biomarkers to follow-up cancer patients. However, the existing biomarkers are often invasive …

Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes.
Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs …

Numerous noninvasive methods are currently being used to determine biomarkers for
diseases such as cancer. However, these methods are not always precise and reliable …

The discovery that all cells secrete extracellular vesicles (EVs) to shuttle proteins and
nucleic acids to recipient cells suggested they play an important role in intercellular …