Biomedical signals and machine learning in amyotrophic lateral sclerosis: a systematic review

F Fernandes, I Barbalho, D Barros, R Valentim… - Biomedical engineering …, 2021 - Springer
Introduction The use of machine learning (ML) techniques in healthcare encompasses an
emerging concept that envisages vast contributions to the tackling of rare diseases. In this …

Machine learning in amyotrophic lateral sclerosis: achievements, pitfalls, and future directions

V Grollemund, PF Pradat, G Querin, F Delbot… - Frontiers in …, 2019 - frontiersin.org
Background: Amyotrophic Lateral Sclerosis (ALS) is a relentlessly progressive
neurodegenerative condition with limited therapeutic options at present. Survival from …

Intersection of network medicine and machine learning towards investigating the key biomarkers and pathways underlying amyotrophic lateral sclerosis: a systematic …

T Das, H Kaur, P Gour, K Prasad… - Briefings in …, 2022 - academic.oup.com
Background Network medicine is an emerging area of research that focuses on delving into
the molecular complexity of the disease, leading to the discovery of network biomarkers and …

[HTML][HTML] Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review

E Tavazzi, E Longato, M Vettoretti, H Aidos… - Artificial Intelligence in …, 2023 - Elsevier
Abstract Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative
disorder characterised by the progressive loss of motor neurons in the brain and spinal cord …

Symptoms timeline and outcomes in amyotrophic lateral sclerosis using artificial intelligence

T Segura, IH Medrano, S Collazo, C Maté, C Sguera… - Scientific Reports, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative motor neuron disease.
Although an early diagnosis is crucial to provide adequate care and improve survival …

[HTML][HTML] Deep learning predictions of survival based on MRI in amyotrophic lateral sclerosis

HK van der Burgh, R Schmidt, HJ Westeneng… - NeuroImage: Clinical, 2017 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large
variation in survival between patients. Currently, it remains rather difficult to predict survival …

From multi-omics approaches to precision medicine in amyotrophic lateral sclerosis

G Morello, S Salomone, V D'Agata… - Frontiers in …, 2020 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disorder,
caused by the degeneration of upper and lower motor neurons for which there is no truly …

Identifying and predicting amyotrophic lateral sclerosis clinical subgroups: a population-based machine-learning study

F Faghri, F Brunn, A Dadu, A Chiò, A Calvo… - The Lancet Digital …, 2022 - thelancet.com
Background Amyotrophic lateral sclerosis (ALS) is known to represent a collection of
overlapping syndromes. Various classification systems based on empirical observations …

Model-based and model-free techniques for amyotrophic lateral sclerosis diagnostic prediction and patient clustering

M Tang, C Gao, SA Goutman, A Kalinin, B Mukherjee… - Neuroinformatics, 2019 - Springer
Amyotrophic lateral sclerosis (ALS) is a complex progressive neurodegenerative disorder
with an estimated prevalence of about 5 per 100,000 people in the United States. In this …

Deep learning methods to predict amyotrophic lateral sclerosis disease progression

C Pancotti, G Birolo, C Rollo, T Sanavia, B Di Camillo… - Scientific reports, 2022 - nature.com
Amyotrophic lateral sclerosis (ALS) is a highly complex and heterogeneous
neurodegenerative disease that affects motor neurons. Since life expectancy is relatively …