Heparan sulfate proteoglycans (HSPGs) are ubiquitously present within the perivascular
basement membrane, and have been shown to be altered in patients with Alzheimer's …

Agrin is a heparan sulfate proteoglycan that is widely expressed in neurons and
microvascular basal lamina in the rodent and avian central nervous system. Agrin induces …

Agrin is an extracellular matrix heparan sulfate proteoglycan (HSPG) well known for its role
in modulation of the neuromuscular junction during development. Although agrin is one of …

Conditions that compromise the blood-brain barrier (BBB) have been increasingly
implicated in the pathogenesis of Alzheimer disease (AD). AGRIN is a heparan sulfate …

Heparan sulfate proteoglycans (HSPGs) have been suggested to play an important role in
the formation and persistence of senile plaques and neurofibrillary tangles in dementia of …

Cerebrovascular deposition of amyloid β protein (Aβ) is a characteristic lesion of Alzheimer's
disease (AD) and hereditary cerebral hemorrhage with amyloidosis of the Dutch type …

Agrin is a heparan sulfate proteoglycan (HSPG) that is highly concentrated in the synaptic
basal lamina at the neuromuscular junction (NMJ). Agrin-like immunoreactiv-ity is also …

In the present study we have identified the extracellular matrix protein agrin as a major
heparan sulfate proteoglycan (HSPG) in embryonic chick brain. Using monoclonal …

The heparan sulfate proteoglycan agrin is responsible for the formation, maintenance, and
regeneration of the neuromuscular junction. In the central nervous system, agrin is widely …

Agrin is a heparan sulfate proteoglycan, which plays an essential role in the development
and maintenance of the neuromuscular junction. Agrin is a stable component of the synaptic …