T Iram, Tabula Muris Consortium - Nature, 2018 - weizmann.elsevierpure.com
Here we present a compendium of single-cell transcriptomic data from the model organism Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These …
Tabula Muris Consortium… - Nature, 2018 - nature.com
Here we present a compendium of single-cell transcriptomic data from the model organism Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These …
Understanding the development and function of an organ requires the characterization of all of its cell types. Traditional methods for visualizing and isolating subpopulations of cells are …
Molecular profiling of single cells has advanced our knowledge of the molecular basis of development. However, current approaches mostly rely on dissociating cells from tissues …
J Cao, DR O'day, HA Pliner, PD Kingsley, M Deng… - Science, 2020 - science.org
INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we set out to generate single-cell atlases of both gene expression (this study) and chromatin …
The Tabula Sapiens Consortium*, RC Jones… - Science, 2022 - science.org
Molecular characterization of cell types using single-cell transcriptome sequencing is revolutionizing cell biology and enabling new insights into the physiology of human organs …
Our understanding of how cells form distinct tissues and organs and interact with each other is limited. Recent single-cell RNA sequencing (scRNA-seq) analyses have described the …
The evolution of gene expression in mammalian organ development remains largely uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …
Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of the three germ layers transform into an embryo that includes most of the major internal and …